Senaste publikationer

  • Artikel i tidskrift

    Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

    Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

    Ingår i American Journal of Clinical Nutrition, s. 110-121, 2020.

    Open access
  • Artikel i tidskrift

    Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

    Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

    Ingår i Bioorganic chemistry (Print), 2020.

  • Artikel i tidskrift

    Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Ingår i European Journal of Pharmacology, 2020.

    Open access
  • Artikel i tidskrift

    Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

    Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

    Ingår i Antimicrobial Agents and Chemotherapy, 2020.

  • Artikel i tidskrift

    Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Ingår i Metabolomics, 2020.

    Open access
  • Artikel i tidskrift

    Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

    A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

    Ingår i Journal of Antimicrobial Chemotherapy, s. 400-408, 2020.

  • Artikel i tidskrift

    Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

    The effect of food on the pharmacokinetics of oral ivermectin

    Ingår i Journal of Antimicrobial Chemotherapy, s. 438-440, 2020.

  • Artikel i tidskrift

    Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

    Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

    Ingår i Antimicrobial Agents and Chemotherapy, 2020.

  • Artikel i tidskrift

    Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

    Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

    Ingår i Clinical Pharmacology and Therapeutics, s. 238-245, 2020.

  • Artikel i tidskrift

    Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Ingår i Growth Hormone & IGF Research, s. 42-47, 2020.

  • Artikel i tidskrift

    Oliw, Ernst H; Hamberg, Mats

    Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

    Ingår i Rapid Communications in Mass Spectrometry, 2020.

  • Artikel i tidskrift

    Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

    Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

    Ingår i Neurobiology of Disease, 2020.

    Open access
  • Artikel i tidskrift

    Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

    Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

    Ingår i Journal of Antimicrobial Chemotherapy, s. 609-617, 2020.

    Open access
  • Artikel i tidskrift

    Selch Larsen, Malte; Vestergaard Juul, Rasmus; Zintner, Shannon M.; Kristensen, Annemarie T. et al.

    Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

    Ingår i Haemophilia, s. 164-172, 2020.

  • Artikel i tidskrift

    Hamm, Gregory R.; Backstrom, Erica; Brulls, Mikael; Nilsson, Anna et al.

    Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging

    Ingår i Journal of Aerosol Medicine, s. 43-53, 2020.

  • Artikel i tidskrift

    Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

    Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

    Ingår i International Journal of Infectious Diseases, s. 133-140, 2020.

    Open access
  • Artikel i tidskrift

    Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Ingår i Oncoimmunology, 2020.

    Open access
  • Artikel i tidskrift

    Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

    Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

    Ingår i Frontiers in Pharmacology, 2020.

    Open access
  • Artikel i tidskrift

    Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Ingår i ChemistryOpen, s. 325-337, 2020.

    Open access
  • Artikel i tidskrift

    Thorsted, Anders; Tano, Eva; Kaivonen, Kia; Sjölin, Jan et al.

    Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime.

    Ingår i Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Doktorsavhandling, sammanläggning

    Lundberg, Stina

    Adolescent behavior: Links to early-life stress and alcohol in male and female rats

    Open access
  • Artikel i tidskrift

    Tanneau, Lénaïg; Karlsson, Mats; Svensson, Elin

    Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis

    Ingår i British Journal of Clinical Pharmacology, s. 913-922, 2020.

    Open access
  • Artikel i tidskrift

    Centanni, Maddalena; Friberg, Lena

    Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

    Ingår i Frontiers in Pharmacology, 2020.

    Open access
  • Artikel i tidskrift

    Arshad, Usman; Ploylearmsaeng, Su-arpa; Karlsson, Mats; Doroshyenko, Oxana et al.

    Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients

    Ingår i Cancer Chemotherapy and Pharmacology, s. 711-722, 2020.

    Open access
  • Artikel i tidskrift

    Wieslander, Håkan; Wählby, Carolina; Spjuth, Ola; Harrison, Philip J et al.

    Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images

    Ingår i IEEE journal of biomedical and health informatics, 2020.

  • Artikel i tidskrift

    Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Ingår i RSC Medicinal chemistry, s. 234-244, 2020.

  • Artikel i tidskrift

    Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

    Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

    Ingår i Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Artikel i tidskrift

    Lundberg, Stina; Nylander, Ingrid; Roman, Erika

    Behavioral profiling in early adolescence and early adulthood of male Wistar rats after short and prolonged maternal separation

    Ingår i Frontiers in Behavioral Neuroscience, 2020.

    Open access
  • Artikel i tidskrift

    Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

    Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

    Ingår i Molecular Pharmaceutics, s. 1458-1469, 2020.

  • Doktorsavhandling, sammanläggning

    Thorsted, Anders

    Pharmacometrics to characterize innate immune response and antibacterial treatments

    Open access
  • Artikel i tidskrift

    Olsson, Anna; Wistrand-Yuen, Pikkei; Nielsen, Elisabet I.; Friberg, Lena et al.

    Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments

    Ingår i Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Artikel i tidskrift

    Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Ingår i Acta Physiologica, 2020.

  • Artikel i tidskrift

    Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

    Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

    Ingår i Frontiers in Chemistry, 2020.

    Open access
  • Artikel i tidskrift

    Nasi, Aikaterini; McArdle, Stephanie; Gaudernack, Gustav; Westman, Gabriel et al.

    Reactive oxygen species as an initiator of toxic innate immune responses inretort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine asearly therapeutic intervention

    Ingår i Toxicology reports, s. 768-771, 2020.

    Open access
  • Artikel i tidskrift

    Abrantes, João A.; Solms, Alexander; Garmann, Dirk; Nielsen, Elisabet I. et al.

    Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

    Ingår i Haematologica, s. 1443-1453, 2020.

    Open access
  • Artikel i tidskrift

    Rostedt Punga, Anna; Strömme, Maria; Alimohammadi, Mohammed; Eltahir, Mohammed et al.

    Flodvåg av långtidssjuka covid-19-patienter väntar

    Ingår i Dagens Nyheter, s. 5-5, 2020.

  • Artikel i tidskrift

    Aggarwal, Tanya; Patil, Sourabh; Ceder, Mikaela; Hayder, Maher et al.

    Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

    Ingår i Frontiers in Physiology, 2020.

    Open access
  • Artikel i tidskrift

    Ceder, Mikaela M.; Lekholm, Emilia; Klaesson, Axel; Tripathi, Rekha et al.

    Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster

    Ingår i Frontiers in Cell and Developmental Biology, 2020.

  • Artikel i tidskrift

    Zhang, Xiaoqun; Mantas, Ioannis; Fridjonsdottir, Elva; Andrén, Per E. et al.

    Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37

    Ingår i Frontiers in Aging Neuroscience, 2020.

    Open access
  • Artikel i tidskrift

    Bivehed, Erik; Gustafsson, Anton; Berglund, Anders; Hellman, Björn

    Evaluation of Potential DNA-Damaging Effects of Nitenpyram and Imidacloprid in Human U937-Cells Using a New Statistical Approach to Analyse Comet Data

    Ingår i EXPOSURE AND HEALTH, s. 547-554, 2020.

    Open access
  • Artikel i tidskrift

    Van Wijk, Rob C; van der Sar, Astrid M; Krekels, Elke H J; Verboom, Theo et al.

    Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translationa lAntituberculosis Drug Development

    Ingår i Clinical and Translational Science, 2020.

    Open access
  • Artikel i tidskrift

    Andronis, Christos; Silva, João Pedro; Lekka, Eftychia; Virvilis, Vassilis et al.

    Molecular basis of mood and cognitive adverse events elucidated via a combination of pharmacovigilance data mining and functional enrichment analysis.

    Ingår i Archives of Toxicology, s. 2829-2845, 2020.

  • Artikel i tidskrift

    Capuccini, Marco; Dahlö, Martin; Toor, Salman; Spjuth, Ola

    MaRe: Processing Big Data with application containers on Apache Spark

    Ingår i GigaScience, 2020.

    Open access
  • Artikel i tidskrift

    Scott, Hayden; Tjernström, Nikita; Roman, Erika

    Effects of pair housing on voluntary alcohol intake in male and female Wistar rats

    Ingår i Alcohol, s. 121-128, 2020.

    Open access
  • Doktorsavhandling, sammanläggning
    A1:107a, Biomedicinskt centrum (BMC), Husargatan 3, Uppsala 2020-10-16 kl 09:15

    Ceder, Mikaela

    Characterization of Novel Solute Carriers in Humans, Mice and Flies: Solute Carriers in a Broad and Narrow Perspective

    Open access
  • Artikel i tidskrift

    Van Wijk, Rob C; Ayoun Alsoud, Rami; Lennernäs, Hans; Simonsson, Ulrika S H

    Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations

    Ingår i Applied Sciences, 2020.

    Open access
  • Artikel i tidskrift

    Kempen, Thomas G. H.; Kälvemark, Amanda; Gillespie, Ulrika; Stewart, Derek

    Comprehensive medication reviews by ward-based pharmacists in Swedish hospitals: What does the patient have to say?

    Ingår i Journal of Evaluation In Clinical Practice, s. 149-157, 2020.

  • Artikel i tidskrift

    Robertson, Luke P.; Moodie, Lindon W. K.; Holland, Darren C.; Jandér, K. Charlotte et al.

    Sulfadiazine Masquerading as a Natural Product from Scilla madeirensis (Scilloideae)

    Ingår i Journal of Natural Products, s. 1305-1308, 2020.

    Open access
  • Artikel i tidskrift

    Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

    Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

    Ingår i Biomolecules, 2020.

    Open access
  • Artikel i tidskrift

    Keutzer, Lina; Simonsson, Ulrika S. H.

    Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example

    Ingår i Frontiers in Pharmacology, 2020.

    Open access