Publications

  • Rofo, Fadi; Yilmaz, Canan Ugur; Metzendorf, Nicole G.; Gustavsson, Tobias et al.

    Enhanced neprilysin-mediated degradation of hippocampal A beta 42 with a somatostatin peptide that enters the brain

    Part of Theranostics, p. 789-804, 2021.

    Open access
  • Vrettou, Maria

    Early life experiences and alcohol use in youth: An emerging role of the Vesicular Glutamate Transporters

    Open access
  • Eriksson, Johanna

    Drug absorption in the lungs: studies in the isolated perfused rat lung model combined with physiologically based biopharmaceutics modelling

    Open access
  • Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

    N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands.

    Part of Bioorganic & Medicinal Chemistry, 2021.

  • Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

    Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

    Part of Methods in Molecular Biology, p. 171-180, 2021.

  • Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

    Part of European Journal of Pharmacology, 2021.

  • Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

    Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

    Part of Science Advances, 2021.

    Open access
  • Ersson, Lisa

    β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity: Studies in vitro and in vivo

  • Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

    Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

    Part of American Journal of Clinical Nutrition, p. 110-121, 2020.

    Open access
  • Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

    Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

    Part of Bioorganic chemistry (Print), 2020.

  • Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

    Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

    A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

    Part of Journal of Antimicrobial Chemotherapy, p. 400-408, 2020.

  • Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

    The effect of food on the pharmacokinetics of oral ivermectin

    Part of Journal of Antimicrobial Chemotherapy, p. 438-440, 2020.

  • Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

    Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

    Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 238-245, 2020.

  • Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Oliw, Ernst H; Hamberg, Mats

    Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

    Part of Rapid Communications in Mass Spectrometry, 2020.

  • Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

    Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

    Part of Neurobiology of Disease, 2020.

    Open access
  • Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

    Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

    Part of Journal of Antimicrobial Chemotherapy, p. 609-617, 2020.

    Open access
  • Selch Larsen, Malte; Vestergaard Juul, Rasmus; Zintner, Shannon M.; Kristensen, Annemarie T. et al.

    Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

    Part of Haemophilia, p. 164-172, 2020.

  • Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

    Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

    Part of International Journal of Infectious Diseases, p. 133-140, 2020.

    Open access
  • Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Part of Oncoimmunology, 2020.

    Open access
  • Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

    Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Part of ChemistryOpen, p. 325-337, 2020.

    Open access
  • Thorsted, Anders; Tano, Eva; Kaivonen, Kia; Sjölin, Jan et al.

    Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime.

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Lundberg, Stina

    Adolescent behavior: Links to early-life stress and alcohol in male and female rats

    Open access
  • Philippot, Gaëtan

    Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs: Experimental studies in mice

    Open access
  • Tanneau, Lénaïg; Karlsson, Mats; Svensson, Elin

    Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis

    Part of British Journal of Clinical Pharmacology, p. 913-922, 2020.

    Open access
  • Centanni, Maddalena; Friberg, Lena

    Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Arshad, Usman; Ploylearmsaeng, Su-arpa; Karlsson, Mats; Doroshyenko, Oxana et al.

    Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients

    Part of Cancer Chemotherapy and Pharmacology, p. 711-722, 2020.

    Open access
  • Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Part of RSC Medicinal chemistry, p. 234-244, 2020.

  • Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

    Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Lundberg, Stina; Nylander, Ingrid; Roman, Erika

    Behavioral profiling in early adolescence and early adulthood of male Wistar rats after short and prolonged maternal separation

    Part of Frontiers in Behavioral Neuroscience, 2020.

    Open access
  • Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

    Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

    Part of Molecular Pharmaceutics, p. 1458-1469, 2020.

  • Thorsted, Anders

    Pharmacometrics to characterize innate immune response and antibacterial treatments

    Open access
  • Olsson, Anna; Wistrand-Yuen, Pikkei; Nielsen, Elisabet I.; Friberg, Lena et al.

    Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Part of Acta Physiologica, 2020.

  • Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

    Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

    Part of Frontiers in Chemistry, 2020.

    Open access
  • Abrantes, João A.; Solms, Alexander; Garmann, Dirk; Nielsen, Elisabet I. et al.

    Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

    Part of Haematologica, p. 1443-1453, 2020.

    Open access
  • Rostedt Punga, Anna; Strömme, Maria; Alimohammadi, Mohammed; Eltahir, Mohammed et al.

    Flodvåg av långtidssjuka covid-19-patienter väntar

    Part of Dagens Nyheter, p. 5-5, 2020.

  • Aggarwal, Tanya; Patil, Sourabh; Ceder, Mikaela; Hayder, Maher et al.

    Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

    Part of Frontiers in Physiology, 2020.

    Open access
  • Zhang, Xiaoqun; Mantas, Ioannis; Fridjonsdottir, Elva; Andrén, Per E. et al.

    Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37

    Part of Frontiers in Aging Neuroscience, 2020.

    Open access
  • Scott, Hayden; Tjernström, Nikita; Roman, Erika

    Effects of pair housing on voluntary alcohol intake in male and female Wistar rats

    Part of Alcohol, p. 121-128, 2020.

    Open access
  • Herman, Stephanie

    Towards an Earlier Detection of Progressive Multiple Sclerosis using Metabolomics and Machine Learning

    Open access
  • Van Wijk, Rob C; Ayoun Alsoud, Rami; Lennernäs, Hans; Simonsson, Ulrika S H

    Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations

    Part of Applied Sciences, 2020.

    Open access
  • Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

    Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

    Part of Biomolecules, 2020.

    Open access
  • Keutzer, Lina; Simonsson, Ulrika S. H.

    Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Tsioumpekou, Maria; Cunha, Sara I.; Ma, Haisha; Åhgren, Aive et al.

    Specific targeting of PDGFR beta in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

    Part of Theranostics, p. 1122-1135, 2020.

    Open access