Publications

  • Stage, Tore Bjerregaard; Wellhagen, Gustaf; Christensen, Mette Marie Hougaard; Guiastrennec, Benjamin et al.

    Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics

    Part of Basic & Clinical Pharmacology & Toxicology, p. 105-114, 2019.

  • Ibrahim, Moustafa M. A.

    Pharmacometric evaluation and improvement of models and study designs - applied in diabetes

    Open access
  • Wyatt, David; Strauss, David; Ray, Balmiki; Mehta, Krina et al.

    Consider ASCPT in Your End-of-Year Giving

    Part of Clinical Pharmacology and Therapeutics, p. 17-21, 2019.

  • Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

    Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

    Part of Neuroscience, p. 172-183, 2019.

    Open access
  • Thörnqvist, Per-Ove; McCarrick, Sarah; Ericsson, Maja; Roman, Erika et al.

    Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish

    Part of Behavioural Brain Research, p. 927-934, 2019.

    Open access
  • Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

    Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

    Part of Journal of Pharmaceutical Sciences, p. 630-640, 2019.

    Open access
  • Ibarra, Cristian; Karlsson, Marie; Codeluppi, Simone; Varas-Godoy, Manuel et al.

    BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

    Part of Molecular Oncology, p. 202-211, 2019.

    Open access
  • Schou, Magnus; Ewing, Par; Cselenyi, Zsolt; Fridén, Markus et al.

    Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator

    Part of EJNMMI Research, 2019.

    Open access
  • Titova, Olga E.

    Metabolic Health and Cognitive Function: The Roles of Lifestyle and Shift Work

    Open access
  • Kempen, Thomas; Hedström, Mariann; Olsson, Hanna; Johansson, Amanda et al.

    Assessment tool for hospital admissions related to medications: development and validation in older patients

    Part of International Journal of Clinical Pharmacy, p. 198-206, 2019.

    Open access
  • Thorsted, Anders; Bouchene, Salim; Tano, Eva; Castegren, Markus et al.

    A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

    Part of PLoS ONE, 2019.

  • Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

    High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

    Part of NeuroImage, p. 881-888, 2019.

  • Kempen, Thomas; Kälvemark, A.; Gillespie, Ulrika; Stewart, D.

    Comprehensive medication reviews in Swedish hospitals: what does the patient have to say?

    Part of International Journal of Clinical Pharmacy, p. 346-346, 2019.

  • Duthaler, Urs; Suenderhauf, Claudia; Karlsson, Mats O; Hussner, Janine et al.

    Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

    Part of British Journal of Clinical Pharmacology, p. 626-633, 2019.

  • Ibrahim, Moustafa M. A.; Ueckert, Sebastian; Freiberga, Svetlana; Kjellsson, Maria C. et al.

    Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment

    Part of AAPS Journal, 2019.

    Open access
  • Ibrahim, Moustafa M. A.; Nordgren, Rikard; Kjellsson, Maria C.; Karlsson, Mats O.

    Variability Attribution for Automated Model Building

    Part of AAPS Journal, 2019.

    Open access
  • Wu, Chi-Chih; Klaesson, Axel; Buskas, Julia; Ranefall, Petter et al.

    In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation

    Part of Journal of Experimental Biology, 2019.

  • Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

    Correlations between sex-related hormones, alcohol dependence and alcohol craving

    Part of Drug And Alcohol Dependence, p. 183-190, 2019.

    Open access
  • Lundberg, Stina; Högman, Cecilia; Roman, Erika

    Adolescent Exploratory Strategies and Behavioral Types in the Multivariate Concentric Square Field (TM) Test

    Part of Frontiers in Behavioral Neuroscience, 2019.

    Open access
  • Herman, Stephanie; Åkerfeldt, Torbjörn; Spjuth, Ola; Burman, Joachim et al.

    Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing-Remitting Multiple Sclerosis

    Part of Cells, 2019.

    Open access
  • Ryeznik, Yevgen

    Optimal adaptive designs and adaptive randomization techniques for clinical trials

    Open access
  • Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

    A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

    Part of ChemistryOpen, p. 114-125, 2019.

    Open access
  • Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

    Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

    Part of American Journal of Psychiatry, p. 146-155, 2019.

  • Zetterström, Andreas; Hämäläinen, Markku D.; Karlberg, Elin; Winkvist, Maria et al.

    Maximum Time Between Tests: A Digital Biomarker to Detect Therapy Compliance and Assess Schedule Quality in Measurement-Based eHealth Systems for Alcohol Use Disorder

    Part of Alcohol and Alcoholism, p. 70-72, 2019.

  • Toxopeus, Eelke L. A.; de Man, Femke M.; Krak, Nanda; Biermann, Katharina et al.

    Association between Paclitaxel Clearance and Tumor Response in Patients with Esophageal Cancer

    Part of Cancers, 2019.

    Open access
  • Ruth, Mike Marvin; Sangen, Jasper J. N.; Remmers, Karlijn; Pennings, Lian J. et al.

    A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria

    Part of Journal of Antimicrobial Chemotherapy, p. 935-943, 2019.

  • Germovsek, Eva; Osborne, Leanne; Gunaratnam, Flora; Lounis, Shehrazed A. et al.

    Development and external evaluation of a population pharmacokinetic model for continuous and intermittent administration of vancomycin in neonates and infants using prospectively collected data

    Part of Journal of Antimicrobial Chemotherapy, p. 1003-1011, 2019.

  • Brekkan, Ari; Lopez-Lazaro, Luis; Plan, Elodie L.; Nyberg, Joakim et al.

    Pharmacokinetic and Pharmacodynamic Sensitivity of Pegfilgrastim

    Part of AAPS Journal, 2019.

  • Gustafsson, Sofia; Sehlin, Dag; Lampa, Erik; Hammarlund-Udenaes, Margareta et al.

    Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development

    Part of Scientific Reports, 2019.

    Open access
  • Kinch, Amelie; Sundström, Christer; Baecklund, Eva; Backlin, Carin et al.

    Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation

    Part of Leukemia and Lymphoma, p. 376-384, 2019.

    Open access
  • Svensson, Robin J.

    Pharmacometric Models to Improve the Treatment and Development of Drugs against Tuberculosis

    Open access
  • Kensert, Alexander; Harrison, Philip J; Spjuth, Ola

    Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes

    Part of SLAS discovery : advancing life sciences R & D, p. 466 466-475 475, 2019.

    Open access
  • Ibrahim, Moustafa M. A.; Largajolli, Anna; Kjellsson, Maria C.; Karlsson, Mats

    Translation between two models; Application with integrated glucose homeostasis models

    Part of Pharmaceutical research, 2019.

    Open access
  • Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

    Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

    Part of Restorative Neurology and Neuroscience, p. 87-96, 2019.

    Open access
  • Peters, Kristian; Bradbury, James; Bergmann, Sven; Capuccini, Marco et al.

    PhenoMeNal: Processing and analysis of metabolomics data in the cloud

    Part of GigaScience, 2019.

    Open access
  • Germovsek, Eva; Ambery, Claire; Yang, Shuying; Beerahee, Misba et al.

    A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT (R) Daily Diary Data from COPD Patients

    Part of AAPS Journal, 2019.

    Open access
  • Maarbjerg, Sabine F.; Thorsted, Anders; Kristoffersson, Anders; Friberg, Lena E. et al.

    Piperacillin pharmacokinetics and target attainment in children with cancer and fever: Can we optimize our dosing strategy?

    Part of Pediatric Blood & Cancer, 2019.

  • van Beek, Stijn W.; ter Heine, Rob; Keizer, Ron J.; Magis-Escurra, Cecile et al.

    Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin

    Part of Clinical Pharmacokinetics, p. 815-826, 2019.

    Open access
  • Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A. David et al.

    Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

    Part of Journal of Alzheimer's Disease, p. 189-197, 2019.

  • Ibrahim, Moustafa M. A.; Largajolli, Anna; Karlsson, Mats; Kjellsson, Maria C.

    The Integrated Glucose Insulin Minimal Model: An improved version

    Part of European Journal of Pharmaceutical Sciences, p. 7-19, 2019.

  • Heldin, Johan; Rubin Sander, Marie; Leino, Mattias; Thomsson, Sara et al.

    Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling

    Part of Experimental Cell Research, p. 69-79, 2019.

    Open access
  • Abrantes, João A.

    Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A

    Open access
  • Brekkan, Ari

    Pharmacometric models in the development of biological medicinal products

    Open access
  • Lampa, Samuel; Dahlö, Martin; Alvarsson, Jonathan; Spjuth, Ola

    SciPipe-Turning Scientific Workflows into Computer Programs

    Part of Computing in science & engineering (Print), p. 109-113, 2019.

  • Hu, Yang; Gaillard, Pieter J.; De lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta

    Targeted Brain Delivery of Methotrexate by Glutathione PEGylated Liposomes: How can the Formulation Make a Difference?

    Part of European journal of pharmaceutics and biopharmaceutics, p. 197-204, 2019.

  • Arshad, Usman; Chasseloup, Estelle; Nordgren, Rikard; Karlsson, Mats O.

    Development of visual predictive checks accounting for multimodal parameter distributions in mixture models

    Part of Journal of Pharmacokinetics and Pharmacodynamics, p. 241-250, 2019.

  • Atis, Muge; Akcan, Ugur; Ugur Yilmaz, Canan; Orhan, Nurcan et al.

    Effects of methyl-beta-cyclodextrin on blood-brain barrier permeability in angiotensin II-induced hypertensive rats

    Part of Brain Research, p. 148-155, 2019.

  • Dhillon, Sundeep S.; Torell, Frida; Donten, Magdalena; Lundstedt-Enkel, Katrin et al.

    Metabolic profiling of zebrafish embryo development from blastula period to early larval stages

    Part of PLoS ONE, 2019.

    Open access
  • Abrantes, João A.; Jönsson, Siv; Karlsson, Mats; Nielsen, Elisabet I.

    Handling interoccasion variability in model-based dose individualization using therapeutic drug monitoring data

    Part of British Journal of Clinical Pharmacology, p. 1326-1336, 2019.

  • Kurland, Siri; Furebring, Mia; Löwdin, Elisabeth; Eliasson, E. et al.

    Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels

    Part of Antimicrobial Agents and Chemotherapy, 2019.