• Rofo, Fadi; Yilmaz, Canan Ugur; Metzendorf, Nicole G.; Gustavsson, Tobias et al.

    Enhanced neprilysin-mediated degradation of hippocampal A beta 42 with a somatostatin peptide that enters the brain

    Part of Theranostics, p. 789-804, 2021.

    Open access
  • Vrettou, Maria

    Early life experiences and alcohol use in youth: An emerging role of the Vesicular Glutamate Transporters

    Open access
  • Eriksson, Johanna

    Drug absorption in the lungs: studies in the isolated perfused rat lung model combined with physiologically based biopharmaceutics modelling

    Open access
  • Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

    Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

    Part of Methods in Molecular Biology, p. 171-180, 2021.

  • Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

    Part of European Journal of Pharmacology, 2021.

  • Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

    Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

    Part of Cellular & Molecular Biology Letters (Druk), 2021.

    Open access
  • Frances-Soriano, Laura; Leino, Mattias; Dos Santos, Marcelina Cardoso; Kovacs, Daniel et al.

    In Situ Rolling Circle Amplification Förster Resonance Energy Transfer (RCA-FRET) for Washing-Free Real-Time Single-Protein Imaging

    Part of Analytical Chemistry, p. 1842-1850, 2021.

  • Gandasi, Nikhil R.; Arapi, Vasiliki; Mickael, Michel E.; Belekar, Prajakta A. et al.

    Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle

    Part of International Journal of Molecular Sciences, 2021.

    Open access
  • Fridjonsdottir, Elva; Shariatgorji, Mohammadreza; Nilsson, Anna; Vallianatou, Theodosia et al.

    Mass spectrometry imaging identifies abnormally elevated brain L-DOPA levels and extrastriatal monoaminergic dysregulation in L-DOPA-induced dyskinesia

    Part of Science Advances, 2021.

    Open access
  • Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

    N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

    Part of Bioorganic & Medicinal Chemistry, 2021.

  • Wieslander, Håkan; Harrison, Philip J.; Skogberg, Gabriel; Jackson, Sonya et al.

    Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images

    Part of IEEE journal of biomedical and health informatics, p. 371-380, 2021.

    Open access
  • Zelleroth, Sofia; Nylander, Erik; Örtenblad, Axel; Stam, Frida et al.

    Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures.

    Part of Journal of Steroid Biochemistry and Molecular Biology, 2021.

  • Eltahir, mohmo394; Fletcher, E.; Dynesius, L.; Jarblad, J. L. et al.

    Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients

    Part of International Immunopharmacology, 2021.

    Open access
  • Rudén, Jonas; Frenning, Göran; Bramer, Tobias; Kyrre, Thalberg et al.

    On the relationship between blend state and dispersibility of adhesive mixtures containing active pharmaceutical ingredients

    Part of International Journal of Pharmaceutics, 2021.

    Open access
  • Germovsek, Eva; Hansson, Anna; Karlsson, Mats O.; Westin, Ake et al.

    A Time-to-Event Model Relating Integrated Craving to Risk of Smoking Relapse Across Different Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 416-423, 2021.

    Open access
  • Blamey, Ben; Toor, Salman; Dahlö, Martin; Wieslander, Håkan et al.

    Rapid development of cloud-native intelligent data pipelines for scientific data streams using the HASTE Toolkit.

    Part of GigaScience, 2021.

    Open access
  • Meier, Silvio R.; Sehlin, Dag; Hultqvist, Greta; Syvänen, Stina

    Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease

    Part of Molecular Imaging and Biology, 2021.

    Open access
  • Lyauk, Yassine Kamal; Jonker, Daniel M.; Hooker, Andrew; Lund, Trine Meldgaard et al.

    Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

    Part of AAPS Journal, 2021.

    Open access
  • Ullah, Junaid; Hashmi, Satwat; Ali, Arslan; Khan, Faisal et al.

    Pericardial fluid proteomic label-free quantification of differentially expressed proteins in ischemic heart disease patients with systolic dysfunction by nano-LC-ESI-MS/MS analysis

    Part of RSC Advances, p. 320-327, 2021.

    Open access
  • Stiller, Christiane; Viktorsson, Kristina; Paz Gomero, Elizabeth; Hååg, Petra et al.

    Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCR

    Part of Cancers, 2021.

    Open access
  • Jarmusch, Scott A.; Lagos-Susaeta, Diego; Diab, Emtinan; Salazar, Oriana et al.

    Iron-meditated fungal starvation by lupine rhizosphere-associated and extremotolerant Streptomyces sp. S29 desferrioxamine production

    Part of MOLECULAR OMICS, p. 95-107, 2021.

    Open access
  • Sharan, Satish; Fang, Lanyan; Lukacova, Viera; Chen, Xiaomei et al.

    Model-Informed Drug Development for Long-Acting Injectable Products: Summary of American College of Clinical Pharmacology Symposium

    Part of Clinical Pharmacology in Drug Development, p. 220-228, 2021.

  • Meier, Silvio R.

    Preclinical PET imaging and therapy of Alzheimer's disease

    Open access
  • Room A1:111, Biomedicinskt Centrum (BMC), Husargatan 3, Uppsala 2021-05-12 10:15

    Rudén, Jonas

    Powder mechanics and dispersion properties of adhesive mixtures for dry powder inhalers: Conceptualized as a blend state model

    Open access
  • He, Jiazhen; You, Huifang; Sandström, Emil; Nittinger, Eva et al.

    Molecular optimization by capturing chemist's intuition using deep neural networks

    Part of Journal of Cheminformatics, 2021.

    Open access
  • Fridjonsdottir, Elva

    Imaging neurochemical changes associated with Parkinson´s disease and L-DOPA-induced dyskinesia using mass spectrometry

    Open access
  • Wilm, Anke; Norinder, Ulf; Agea, M. Isabel; Kops, Christina de Bruyn et al.

    Skin Doctor CP: Conformal Prediction of the Skin Sensitization Potential of Small Organic Molecules

    Part of Chemical Research in Toxicology, p. 330-344, 2021.

    Open access
  • Waldenströmsalen, Rudbeck Laboratory, Dag Hammarskjölds Väg 20, Uppsala 2021-05-21 09:00

    Eltahir, Mohamed

    Antibody-based Cancer Immunotherapy: Personalization, response prediction and safety considerations

    Open access
  • El-Garawani, Islam M.; Shaheen, Eman M.; El-Seedi, Hesham R.; Khalifa, Shaden A. M. et al.

    Angiotensinogen Gene Missense Polymorphisms (rs699 and rs4762): The Association of End-Stage Renal Failure Risk with Type 2 Diabetes and Hypertension in Egyptians

    Part of Genes, 2021.

    Open access
  • Fellström, Bengt; Helmersson Karlqvist, Johanna; Lind, Lars; Soveri, Inga et al.

    Albumin Urinary Excretion Is Associated with Increased Levels of Urinary Chemokines, Cytokines, and Growth Factors Levels in Humans.

    Part of Biomolecules, 2021.

    Open access
  • El-Aarag, Bishoy; El-Saied, Fathy; Salem, Tarek; Khedr, Nesrin et al.

    New metal complexes derived from diacetylmonoxime-n(4) antipyrinylthiosemicarbazone: Synthesis, characterization and evaluation of antitumor activity against Ehrlich solid tumors induced in mice

    Part of Arabian Journal of Chemistry, 2021.

    Open access
  • Xu, Zhe; Fan, Fengjiao; Chen, Hui; Shi, Pujie et al.

    Absorption and transport of a Mytilus edulis-derived peptide with the function of preventing osteoporosis

    Part of Food & Function, p. 2102-2111, 2021.

  • Pieterman, E. D.; van den Berg, S.; van der Meijden, A.; Svensson, Elin et al.

    Higher Dosing of Rifamycins Does Not Increase Activity against Mycobacterium tuberculosis in the Hollow-Fiber Infection Model

    Part of Antimicrobial Agents and Chemotherapy, 2021.

  • Ibrahim, Moustafa M. A.; Redestad, Erik; Kjellsson, Maria C.

    Optimal Designs for Model-Based Assessment of Insulin Sensitivity and Glucose Effectiveness.

    Part of Journal of clinical pharmacology, p. 116-124, 2021.

    Open access
  • Ersson, Lisa

    β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity: Studies in vitro and in vivo

  • Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

    Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

    Part of American Journal of Clinical Nutrition, p. 110-121, 2020.

    Open access
  • Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

    Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

    Part of Bioorganic chemistry (Print), 2020.

  • Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

    Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

    A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

    Part of Journal of Antimicrobial Chemotherapy, p. 400-408, 2020.

  • Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

    The effect of food on the pharmacokinetics of oral ivermectin

    Part of Journal of Antimicrobial Chemotherapy, p. 438-440, 2020.

  • Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

    Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

    Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 238-245, 2020.

  • Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Oliw, Ernst H; Hamberg, Mats

    Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

    Part of Rapid Communications in Mass Spectrometry, 2020.

  • Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

    Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

    Part of Journal of Antimicrobial Chemotherapy, p. 609-617, 2020.

    Open access
  • Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

    Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

    Part of International Journal of Infectious Diseases, p. 133-140, 2020.

    Open access
  • Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Part of Oncoimmunology, 2020.

    Open access
  • Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

    Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

    Part of Frontiers in Pharmacology, 2020.

    Open access