Publications

  • Ersson, Lisa

    β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity: Studies in vitro and in vivo

  • Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

    Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

    Part of American Journal of Clinical Nutrition, p. 110-121, 2020.

    Open access
  • Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

    Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

    Part of Bioorganic chemistry (Print), 2020.

  • Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Tsioumpekou, Maria; Cunha, Sara I.; Ma, Haisha; Åhgren, Aive et al.

    Specific targeting of PDGFR beta in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

    Part of Theranostics, p. 1122-1135, 2020.

    Open access
  • Aggarwal, Tanya; Patil, Sourabh; Eriksson, Mikaela; Hayder, Maher et al.

    Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

    Part of Frontiers in Physiology, 2020.

    Open access
  • Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

    Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

    A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

    Part of Journal of Antimicrobial Chemotherapy, p. 400-408, 2020.

  • Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

    The effect of food on the pharmacokinetics of oral ivermectin

    Part of Journal of Antimicrobial Chemotherapy, p. 438-440, 2020.

  • Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

    Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

    Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

    Part of Clinical Pharmacology and Therapeutics, p. 238-245, 2020.

  • Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Oliw, Ernst H; Hamberg, Mats

    Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

    Part of Rapid Communications in Mass Spectrometry, 2020.

  • Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

    Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

    Part of Neurobiology of Disease, 2020.

    Open access
  • Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

    Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

    Part of Journal of Antimicrobial Chemotherapy, p. 609-617, 2020.

    Open access
  • Klastrup, Vibeke; Thorsted, Anders; Storgaard, Merete; Christensen, Steffen et al.

    Population pharmacokinetics of piperacillin following continuous infusion in critically ill patients: Impact of renal function on target attainment

    Part of Antimicrobial Agents and Chemotherapy, 2020.

  • Selch Larsen, Malte; Vestergaard Juul, Rasmus; Zintner, Shannon M.; Kristensen, Annemarie T. et al.

    Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

    Part of Haemophilia, p. 164-172, 2020.

  • Hamm, Gregory R.; Backstrom, Erica; Brulls, Mikael; Nilsson, Anna et al.

    Revealing the Regional Localization and Differential Lung Retention of Inhaled Compounds by Mass Spectrometry Imaging

    Part of Journal of Aerosol Medicine, p. 43-53, 2020.

  • Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

    Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

    Part of International Journal of Infectious Diseases, p. 133-140, 2020.

    Open access
  • Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Part of Oncoimmunology, 2020.

    Open access
  • Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

    Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Part of ChemistryOpen, p. 325-337, 2020.

    Open access
  • Thorsted, Anders; Tano, Eva; Kaivonen, Kia; Sjölin, Jan et al.

    Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime.

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Lundberg, Stina

    Adolescent behavior: Links to early-life stress and alcohol in male and female rats

    Open access
  • Philippot, Gaëtan

    Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs: Experimental studies in mice

    Open access
  • Tanneau, Lénaïg; Karlsson, Mats; Svensson, Elin

    Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis

    Part of British Journal of Clinical Pharmacology, p. 913-922, 2020.

    Open access
  • Centanni, Maddalena; Friberg, Lena

    Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

    Part of Frontiers in Pharmacology, 2020.

    Open access
  • Arshad, Usman; Ploylearmsaeng, Su-arpa; Karlsson, Mats; Doroshyenko, Oxana et al.

    Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients

    Part of Cancer Chemotherapy and Pharmacology, p. 711-722, 2020.

    Open access
  • Wieslander, Håkan; Wählby, Carolina; Spjuth, Ola; Harrison, Philip J et al.

    Deep learning and conformal prediction for hierarchical analysis of large-scale whole-slide tissue images

    Part of IEEE journal of biomedical and health informatics, 2020.

  • Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Part of RSC Medicinal chemistry, p. 234-244, 2020.

  • Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

    Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Scott, Hayden; Tjernström, Nikita; Roman, Erika

    Effects of pair housing on voluntary alcohol intake in male and female Wistar rats.

    Part of Alcohol, p. 121-128, 2020.

  • Lundberg, Stina; Nylander, Ingrid; Roman, Erika

    Behavioral profiling in early adolescence and early adulthood of male Wistar rats after short and prolonged maternal separation

    Part of Frontiers in Behavioral Neuroscience, 2020.

    Open access
  • Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

    Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

    Part of Molecular Pharmaceutics, p. 1458-1469, 2020.

  • Thorsted, Anders

    Pharmacometrics to characterize innate immune response and antibacterial treatments

    Open access
  • Olsson, Anna; Wistrand-Yuen, Pikkei; Nielsen, Elisabet I.; Friberg, Lena et al.

    Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments

    Part of Antimicrobial Agents and Chemotherapy, 2020.

    Open access
  • Hovén, Emma; Ljung, Rickard; Ljungman, Gustaf; Ljungman, Lisa et al.

    Increased risk of mental health problems after cancer during adolescence: a register based cohort study.

    Part of International Journal of Cancer, 2020.

  • Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Part of Acta Physiologica, 2020.

  • Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

    Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

    Part of Frontiers in Chemistry, 2020.

    Open access
  • Nasi, Aikaterini; McArdle, Stephanie; Gaudernack, Gustav; Westman, Gabriel et al.

    Reactive oxygen species as an initiator of toxic innate immune responses inretort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine asearly therapeutic intervention

    Part of Toxicology reports, p. 768-771, 2020.

    Open access
  • Abrantes, João A.; Solms, Alexander; Garmann, Dirk; Nielsen, Elisabet I. et al.

    Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

    Part of Haematologica, p. 1443-1453, 2020.

    Open access
  • Stage, Tore Bjerregaard; Wellhagen, Gustaf; Christensen, Mette Marie Hougaard; Guiastrennec, Benjamin et al.

    Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics

    Part of Basic & Clinical Pharmacology & Toxicology, p. 105-114, 2019.

  • Wyatt, David; Strauss, David; Ray, Balmiki; Mehta, Krina et al.

    Consider ASCPT in Your End-of-Year Giving

    Part of Clinical Pharmacology and Therapeutics, p. 17-21, 2019.

  • Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

    Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

    Part of Neuroscience, p. 172-183, 2019.

    Open access
  • Thörnqvist, Per-Ove; McCarrick, Sarah; Ericsson, Maja; Roman, Erika et al.

    Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish

    Part of Behavioural Brain Research, p. 927-934, 2019.

    Open access
  • Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

    Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

    Part of Journal of Pharmaceutical Sciences, p. 630-640, 2019.

    Open access
  • Ibarra, Cristian; Karlsson, Marie; Codeluppi, Simone; Varas-Godoy, Manuel et al.

    BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

    Part of Molecular Oncology, p. 202-211, 2019.

    Open access
  • Schou, Magnus; Ewing, Par; Cselenyi, Zsolt; Fridén, Markus et al.

    Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator

    Part of EJNMMI Research, 2019.

    Open access
  • Titova, Olga E.

    Metabolic Health and Cognitive Function: The Roles of Lifestyle and Shift Work

    Open access