Publikationer

Ersson, Lisa

β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity: Studies in vitro and in vivo

Till DiVA

Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

Ingår i American Journal of Clinical Nutrition, s. 110-121, 2020.

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Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

Ingår i Bioorganic chemistry (Print), 2020.

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Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Ingår i European Journal of Pharmacology, 2020.

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Tsioumpekou, Maria; Cunha, Sara I.; Ma, Haisha; Åhgren, Aive et al.

Specific targeting of PDGFR beta in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

Ingår i Theranostics, s. 1122-1135, 2020.

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Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

Growth hormone increases dendritic spine density in primary hippocampal cell cultures

Ingår i Growth Hormone & IGF Research, s. 42-47, 2020.

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Stage, Tore Bjerregaard; Wellhagen, Gustaf; Christensen, Mette Marie Hougaard; Guiastrennec, Benjamin et al.

Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics

Ingår i Basic & Clinical Pharmacology & Toxicology, s. 105-114, 2019.

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Ibrahim, Moustafa M. A.

Pharmacometric evaluation and improvement of models and study designs - applied in diabetes

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Wyatt, David; Strauss, David; Ray, Balmiki; Mehta, Krina et al.

Consider ASCPT in Your End-of-Year Giving

Ingår i Clinical Pharmacology and Therapeutics, s. 17-21, 2019.

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Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

Ingår i Neuroscience, s. 172-183, 2019.

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Thörnqvist, Per-Ove; McCarrick, Sarah; Ericsson, Maja; Roman, Erika et al.

Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish

Ingår i Behavioural Brain Research, s. 927-934, 2019.

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Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

Ingår i Journal of Pharmaceutical Sciences, s. 630-640, 2019.

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Ibarra, Cristian; Karlsson, Marie; Codeluppi, Simone; Varas-Godoy, Manuel et al.

BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

Ingår i Molecular Oncology, s. 202-211, 2019.

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Schou, Magnus; Ewing, Par; Cselenyi, Zsolt; Fridén, Markus et al.

Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator

Ingår i EJNMMI Research, 2019.

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Titova, Olga E.

Metabolic Health and Cognitive Function: The Roles of Lifestyle and Shift Work

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Kempen, Thomas; Hedström, Mariann; Olsson, Hanna; Johansson, Amanda et al.

Assessment tool for hospital admissions related to medications: development and validation in older patients

Ingår i International Journal of Clinical Pharmacy, s. 198-206, 2019.

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Thorsted, Anders; Bouchene, Salim; Tano, Eva; Castegren, Markus et al.

A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

Ingår i PLoS ONE, 2019.

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Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

Ingår i NeuroImage, s. 881-888, 2019.

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Kempen, Thomas; Kälvemark, A.; Gillespie, Ulrika; Stewart, D.

Comprehensive medication reviews in Swedish hospitals: what does the patient have to say?

Ingår i International Journal of Clinical Pharmacy, s. 346-346, 2019.

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Duthaler, Urs; Suenderhauf, Claudia; Karlsson, Mats O; Hussner, Janine et al.

Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

Ingår i British Journal of Clinical Pharmacology, s. 626-633, 2019.

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Ibrahim, Moustafa M. A.; Ueckert, Sebastian; Freiberga, Svetlana; Kjellsson, Maria C. et al.

Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment

Ingår i AAPS Journal, 2019.

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Ibrahim, Moustafa M. A.; Nordgren, Rikard; Kjellsson, Maria C.; Karlsson, Mats O.

Variability Attribution for Automated Model Building

Ingår i AAPS Journal, 2019.

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Wu, Chi-Chih; Klaesson, Axel; Buskas, Julia; Ranefall, Petter et al.

In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation

Ingår i Journal of Experimental Biology, 2019.

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Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

Correlations between sex-related hormones, alcohol dependence and alcohol craving

Ingår i Drug And Alcohol Dependence, s. 183-190, 2019.

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Lundberg, Stina; Högman, Cecilia; Roman, Erika

Adolescent Exploratory Strategies and Behavioral Types in the Multivariate Concentric Square Field (TM) Test

Ingår i Frontiers in Behavioral Neuroscience, 2019.

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Herman, Stephanie; Åkerfeldt, Torbjörn; Spjuth, Ola; Burman, Joachim et al.

Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing-Remitting Multiple Sclerosis

Ingår i Cells, 2019.

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Ryeznik, Yevgen

Optimal adaptive designs and adaptive randomization techniques for clinical trials

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Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

Ingår i ChemistryOpen, s. 114-125, 2019.

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Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

Ingår i American Journal of Psychiatry, s. 146-155, 2019.

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Zetterström, Andreas; Hämäläinen, Markku D.; Karlberg, Elin; Winkvist, Maria et al.

Maximum Time Between Tests: A Digital Biomarker to Detect Therapy Compliance and Assess Schedule Quality in Measurement-Based eHealth Systems for Alcohol Use Disorder

Ingår i Alcohol and Alcoholism, s. 70-72, 2019.

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Toxopeus, Eelke L. A.; de Man, Femke M.; Krak, Nanda; Biermann, Katharina et al.

Association between Paclitaxel Clearance and Tumor Response in Patients with Esophageal Cancer

Ingår i Cancers, 2019.

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Ruth, Mike Marvin; Sangen, Jasper J. N.; Remmers, Karlijn; Pennings, Lian J. et al.

A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria

Ingår i Journal of Antimicrobial Chemotherapy, s. 935-943, 2019.

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Germovsek, Eva; Osborne, Leanne; Gunaratnam, Flora; Lounis, Shehrazed A. et al.

Development and external evaluation of a population pharmacokinetic model for continuous and intermittent administration of vancomycin in neonates and infants using prospectively collected data

Ingår i Journal of Antimicrobial Chemotherapy, s. 1003-1011, 2019.

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Brekkan, Ari; Lopez-Lazaro, Luis; Plan, Elodie L.; Nyberg, Joakim et al.

Pharmacokinetic and Pharmacodynamic Sensitivity of Pegfilgrastim

Ingår i AAPS Journal, 2019.

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Gustafsson, Sofia; Sehlin, Dag; Lampa, Erik; Hammarlund-Udenaes, Margareta et al.

Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development

Ingår i Scientific Reports, 2019.

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Svensson, Robin J.

Pharmacometric Models to Improve the Treatment and Development of Drugs against Tuberculosis

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Kensert, Alexander; Harrison, Philip J; Spjuth, Ola

Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes

Ingår i SLAS discovery : advancing life sciences R & D, s. 466 466-475 475, 2019.

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Ibrahim, Moustafa M. A.; Largajolli, Anna; Kjellsson, Maria C.; Karlsson, Mats

Translation between two models; Application with integrated glucose homeostasis models

Ingår i Pharmaceutical research, 2019.

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Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

Ingår i Restorative Neurology and Neuroscience, s. 87-96, 2019.

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Germovsek, Eva; Ambery, Claire; Yang, Shuying; Beerahee, Misba et al.

A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT (R) Daily Diary Data from COPD Patients

Ingår i AAPS Journal, 2019.

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Maarbjerg, Sabine F.; Thorsted, Anders; Kristoffersson, Anders; Friberg, Lena E. et al.

Piperacillin pharmacokinetics and target attainment in children with cancer and fever: Can we optimize our dosing strategy?

Ingår i Pediatric Blood & Cancer, 2019.

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van Beek, Stijn W.; ter Heine, Rob; Keizer, Ron J.; Magis-Escurra, Cecile et al.

Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin

Ingår i Clinical Pharmacokinetics, s. 815-826, 2019.

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Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A. David et al.

Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

Ingår i Journal of Alzheimer's Disease, s. 189-197, 2019.

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Ibrahim, Moustafa M. A.; Largajolli, Anna; Karlsson, Mats; Kjellsson, Maria C.

The Integrated Glucose Insulin Minimal Model: An improved version

Ingår i European Journal of Pharmaceutical Sciences, s. 7-19, 2019.

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Heldin, Johan; Rubin Sander, Marie; Leino, Mattias; Thomsson, Sara et al.

Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling

Ingår i Experimental Cell Research, s. 69-79, 2019.

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Abrantes, João A.

Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A

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Brekkan, Ari

Pharmacometric models in the development of biological medicinal products

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Lampa, Samuel; Dahlö, Martin; Alvarsson, Jonathan; Spjuth, Ola

SciPipe-Turning Scientific Workflows into Computer Programs

Ingår i Computing in science & engineering (Print), s. 109-113, 2019.

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Hu, Yang; Gaillard, Pieter J.; De lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta

Targeted Brain Delivery of Methotrexate by Glutathione PEGylated Liposomes: How can the Formulation Make a Difference?

Ingår i European journal of pharmaceutics and biopharmaceutics, s. 197-204, 2019.

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Arshad, Usman; Chasseloup, Estelle; Nordgren, Rikard; Karlsson, Mats O.

Development of visual predictive checks accounting for multimodal parameter distributions in mixture models

Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 241-250, 2019.

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