Publikationer

Rofo, Fadi; Yilmaz, Canan Ugur; Metzendorf, Nicole G.; Gustavsson, Tobias et al.

Enhanced neprilysin-mediated degradation of hippocampal A beta 42 with a somatostatin peptide that enters the brain

Ingår i Theranostics, s. 789-804, 2021.

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Alvarsson, Jonathan; Arvidsson Mc Shane, Staffan; Norinder, Ulf; Spjuth, Ola

Predicting With Confidence: Using Conformal Prediction in Drug Discovery.

Ingår i Journal of Pharmaceutical Sciences, s. 42-49, 2021.

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Vrettou, Maria

Early life experiences and alcohol use in youth: An emerging role of the Vesicular Glutamate Transporters

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Eriksson, Johanna

Drug absorption in the lungs: studies in the isolated perfused rat lung model combined with physiologically based biopharmaceutics modelling

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Ersson, Lisa

β-N-methylamino-L-alanine (BMAA)-induced neurotoxicity: Studies in vitro and in vivo

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Vora, Bianca; Green, Elizabeth A. E.; Khuri, Natalia; Bällgren, Frida et al.

Drug-nutrient interactions: discovering prescription drug inhibitors of the thiamine transporter ThTR-2 (SLC19A3)

Ingår i American Journal of Clinical Nutrition, s. 110-121, 2020.

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Zarei, Omid; Sarri, Niki; Dastmalchi, Siavoush; Zokai, Fateme et al.

Structure-based discovery of novel small molecule inhibitors of platelet-derived growth factor-B

Ingår i Bioorganic chemistry (Print), 2020.

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Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

Ingår i European Journal of Pharmacology, 2020.

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Llanos-Paez, Carolina C.; Staatz, C. E.; Lawson, R.; Hennig, S.

Differences in the Pharmacokinetics of Gentamicin between Oncology and Nononcology Pediatric Patients

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

Ingår i Metabolomics, 2020.

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Kristoffersson, Anders N.; Bissantz, Caterina; Okujava, Rusudan; Haldimann, Andreas et al.

A novel mechanism-based pharmacokinetic-pharmacodynamic (PKPD) model describing ceftazidime/avibactam efficacy against β-lactamase-producing Gram-negative bacteria

Ingår i Journal of Antimicrobial Chemotherapy, s. 400-408, 2020.

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Duthaler, Urs; Leisegang, Rory; Karlsson, Mats; Krähenbühl, Stephan et al.

The effect of food on the pharmacokinetics of oral ivermectin

Ingår i Journal of Antimicrobial Chemotherapy, s. 438-440, 2020.

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Nyberg, Henrik B.; Draper, Heather R.; Garcia-Prats, Anthony J.; Thee, Stephanie et al.

Population Pharmacokinetics and Dosing of Ethionamide in Children with Tuberculosis

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Germovsek, Eva; Hansson, Anna; Kjellsson, Maria C.; Perez Ruixo, Juan Jose et al.

Relating Nicotine Plasma Concentration to Momentary Craving Across Four Nicotine Replacement Therapy Formulations

Ingår i Clinical Pharmacology and Therapeutics, s. 238-245, 2020.

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Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

Growth hormone increases dendritic spine density in primary hippocampal cell cultures

Ingår i Growth Hormone & IGF Research, s. 42-47, 2020.

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Oliw, Ernst H; Hamberg, Mats

Charge migration fragmentation in the negative ion mode of cyclopentenone and cyclopentanone intermediates in the biosynthesis of jasmonates

Ingår i Rapid Communications in Mass Spectrometry, 2020.

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Hulme, Heather; Fridjonsdottir, Elva; Gunnarsdottir, Halla; Vallianatou, Theodosia et al.

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Ingår i Neurobiology of Disease, 2020.

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Ruth, Mike Marvin; Koeken, Valerie A. C. M.; Pennings, Lian J.; Svensson, Elin et al.

Is there a role for tedizolid in the treatment of non-tuberculous mycobacterial disease?

Ingår i Journal of Antimicrobial Chemotherapy, s. 609-617, 2020.

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Selch Larsen, Malte; Vestergaard Juul, Rasmus; Zintner, Shannon M.; Kristensen, Annemarie T. et al.

Rotational thromboelastometry can predict the probability of bleeding events in a translational rat model of haemophilia A following gene-based FVIIa prophylaxis

Ingår i Haemophilia, s. 164-172, 2020.

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Bue, Mats; Sou, Tomás; Okkels, Anna S. L.; Hanberg, Pelle et al.

Population pharmacokinetics of piperacillin in plasma and subcutaneous tissue in patients on continuous renal replacement therapy

Ingår i International Journal of Infectious Diseases, s. 133-140, 2020.

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Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

Ingår i Oncoimmunology, 2020.

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Schintu, Nicoletta; Zhang, Xiaoqun; Stroth, Nikolas; Mathé, Aleksander A. et al.

Non-dopaminergic Alterations in Depression-Like FSL Rats in Experimental Parkinsonism and L-DOPA Responses

Ingår i Frontiers in Pharmacology, 2020.

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Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

Ingår i ChemistryOpen, s. 325-337, 2020.

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Thorsted, Anders; Tano, Eva; Kaivonen, Kia; Sjölin, Jan et al.

Extension of Pharmacokinetic/Pharmacodynamic Time-Kill Studies To Include Lipopolysaccharide/Endotoxin Release from Escherichia coli Exposed to Cefuroxime.

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Lundberg, Stina

Adolescent behavior: Links to early-life stress and alcohol in male and female rats

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Philippot, Gaëtan

Neurodevelopmental Consequences of Exposure to Paracetamol (Acetaminophen) and Related Drugs: Experimental studies in mice

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Tanneau, Lénaïg; Karlsson, Mats; Svensson, Elin

Understanding the drug exposure-response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug-resistant tuberculosis

Ingår i British Journal of Clinical Pharmacology, s. 913-922, 2020.

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Centanni, Maddalena; Friberg, Lena

Model-Based Biomarker Selection for Dose Individualization of Tyrosine-Kinase Inhibitors

Ingår i Frontiers in Pharmacology, 2020.

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Arshad, Usman; Ploylearmsaeng, Su-arpa; Karlsson, Mats; Doroshyenko, Oxana et al.

Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic-pharmacodynamic model in gastrointestinal cancer patients

Ingår i Cancer Chemotherapy and Pharmacology, s. 711-722, 2020.

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Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

Ingår i RSC Medicinal chemistry, s. 234-244, 2020.

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Faraj, Alan; Svensson, Robin J.; Diacon, Andreas H.; Simonsson, Ulrika S H

Drug Effect of Clofazimine on Persisters Explains an Unexpected Increase in Bacterial Load in Patients

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Lundberg, Stina; Nylander, Ingrid; Roman, Erika

Behavioral profiling in early adolescence and early adulthood of male Wistar rats after short and prolonged maternal separation

Ingår i Frontiers in Behavioral Neuroscience, 2020.

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Sou, Tomás; Kukavica-Ibrulj, Irena; Levesque, Roger C.; Friberg, Lena et al.

Model-Informed Drug Development in Pulmonary Delivery: Semimechanistic Pharmacokinetic-Pharmacodynamic Modeling for Evaluation of Treatments against Chronic Pseudomonas aeruginosa Lung Infections

Ingår i Molecular Pharmaceutics, s. 1458-1469, 2020.

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Thorsted, Anders

Pharmacometrics to characterize innate immune response and antibacterial treatments

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Olsson, Anna; Wistrand-Yuen, Pikkei; Nielsen, Elisabet I.; Friberg, Lena et al.

Efficacy of Antibiotic Combinations against Multidrug-Resistant Pseudomonas aeruginosa in Automated Time-Lapse Microscopy and Static Time-Kill Experiments

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Nyberg, Fred; Hallberg, Mathias

Growing knowledge: How growth hormone improves learning

Ingår i Acta Physiologica, 2020.

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Soukarieh, Fadi; Liu, Ruiling; Romero, Manuel; Roberston, Shaun N. et al.

Hit Identification of New Potent PqsR Antagonists as Inhibitors of Quorum Sensing in Planktonic and Biofilm Grown Pseudomonas aeruginosa

Ingår i Frontiers in Chemistry, 2020.

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Abrantes, João A.; Solms, Alexander; Garmann, Dirk; Nielsen, Elisabet I. et al.

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients

Ingår i Haematologica, s. 1443-1453, 2020.

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Rostedt Punga, Anna; Strömme, Maria; Alimohammadi, Mohammed; Eltahir, Mohammed et al.

Flodvåg av långtidssjuka covid-19-patienter väntar

Ingår i Dagens Nyheter, s. 5-5, 2020.

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Aggarwal, Tanya; Patil, Sourabh; Ceder, Mikaela; Hayder, Maher et al.

Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

Ingår i Frontiers in Physiology, 2020.

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Zhang, Xiaoqun; Mantas, Ioannis; Fridjonsdottir, Elva; Andrén, Per E. et al.

Deficits in Motor Performance, Neurotransmitters and Synaptic Plasticity in Elderly and Experimental Parkinsonian Mice Lacking GPR37

Ingår i Frontiers in Aging Neuroscience, 2020.

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Scott, Hayden; Tjernström, Nikita; Roman, Erika

Effects of pair housing on voluntary alcohol intake in male and female Wistar rats

Ingår i Alcohol, s. 121-128, 2020.

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Herman, Stephanie

Towards an Earlier Detection of Progressive Multiple Sclerosis using Metabolomics and Machine Learning

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Van Wijk, Rob C; Ayoun Alsoud, Rami; Lennernäs, Hans; Simonsson, Ulrika S H

Model-informed drug discovery and development strategy for the rapid development of anti-tuberculosis drug combinations

Ingår i Applied Sciences, 2020.

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Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

Ingår i Biomolecules, 2020.

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Keutzer, Lina; Simonsson, Ulrika S. H.

Individualized Dosing With High Inter-Occasion Variability Is Correctly Handled With Model-Informed Precision Dosing: Using Rifampicin as an Example

Ingår i Frontiers in Pharmacology, 2020.

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Tsioumpekou, Maria; Cunha, Sara I.; Ma, Haisha; Åhgren, Aive et al.

Specific targeting of PDGFR beta in the stroma inhibits growth and angiogenesis in tumors with high PDGF-BB expression

Ingår i Theranostics, s. 1122-1135, 2020.

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van der Wouden, Cathelijne H.; Bohringer, Stefan; Cecchin, Erika; Cheung, Ka-Chun et al.

Generating evidence for precision medicine: considerations made by the Ubiquitous Pharmacogenomics Consortium when designing and operationalizing the PREPARE study

Ingår i Pharmacogenetics & Genomics, s. 131-144, 2020.

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Klastrup, Vibeke; Thorsted, Anders; Storgaard, Merete; Christensen, Steffen et al.

Population Pharmacokinetics of Piperacillin following Continuous Infusion in Critically Ill Patients and Impact of Renal Function on Target Attainment

Ingår i Antimicrobial Agents and Chemotherapy, 2020.

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Hovén, Emma; Ljung, Rickard; Ljungman, Gustaf; Ljungman, Lisa et al.

Increased risk of mental health problems after cancer during adolescence: a register based cohort study.

Ingår i International Journal of Cancer, 2020.

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