Publikationer

  • Stage, Tore Bjerregaard; Wellhagen, Gustaf; Christensen, Mette Marie Hougaard; Guiastrennec, Benjamin et al.

    Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics

    Ingår i Basic & Clinical Pharmacology & Toxicology, s. 105-114, 2019.

  • Ibrahim, Moustafa M. A.

    Pharmacometric evaluation and improvement of models and study designs - applied in diabetes

    Open access
  • Wyatt, David; Strauss, David; Ray, Balmiki; Mehta, Krina et al.

    Consider ASCPT in Your End-of-Year Giving

    Ingår i Clinical Pharmacology and Therapeutics, s. 17-21, 2019.

  • Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

    Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

    Ingår i Neuroscience, s. 172-183, 2019.

    Open access
  • Thörnqvist, Per-Ove; McCarrick, Sarah; Ericsson, Maja; Roman, Erika et al.

    Bold zebrafish (Danio rerio) express higher levels of delta opioid and dopamine D2 receptors in the brain compared to shy fish

    Ingår i Behavioural Brain Research, s. 927-934, 2019.

    Open access
  • Sou, Tomás; Kukavica-Ibrulj, Irena; Soukarieh, Fadi; Halliday, Nigel et al.

    Model-Based Drug Development in Pulmonary Delivery: Pharmacokinetic Analysis of Novel Drug Candidates for Treatment of Pseudomonas aeruginosa Lung Infection

    Ingår i Journal of Pharmaceutical Sciences, s. 630-640, 2019.

    Open access
  • Ibarra, Cristian; Karlsson, Marie; Codeluppi, Simone; Varas-Godoy, Manuel et al.

    BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

    Ingår i Molecular Oncology, s. 202-211, 2019.

    Open access
  • Schou, Magnus; Ewing, Par; Cselenyi, Zsolt; Fridén, Markus et al.

    Pulmonary PET imaging confirms preferential lung target occupancy of an inhaled bronchodilator

    Ingår i EJNMMI Research, 2019.

    Open access
  • Titova, Olga E.

    Metabolic Health and Cognitive Function: The Roles of Lifestyle and Shift Work

    Open access
  • Kempen, Thomas; Hedström, Mariann; Olsson, Hanna; Johansson, Amanda et al.

    Assessment tool for hospital admissions related to medications: development and validation in older patients

    Ingår i International Journal of Clinical Pharmacy, s. 198-206, 2019.

    Open access
  • Thorsted, Anders; Bouchene, Salim; Tano, Eva; Castegren, Markus et al.

    A non-linear mixed effect model for innate immune response: In vivo kinetics of endotoxin and its induction of the cytokines tumor necrosis factor alpha and interleukin-6

    Ingår i PLoS ONE, 2019.

  • Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

    High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

    Ingår i NeuroImage, s. 881-888, 2019.

  • Kempen, Thomas; Kälvemark, A.; Gillespie, Ulrika; Stewart, D.

    Comprehensive medication reviews in Swedish hospitals: what does the patient have to say?

    Ingår i International Journal of Clinical Pharmacy, s. 346-346, 2019.

  • Duthaler, Urs; Suenderhauf, Claudia; Karlsson, Mats O; Hussner, Janine et al.

    Population pharmacokinetics of oral ivermectin in venous plasma and dried blood spots in healthy volunteers

    Ingår i British Journal of Clinical Pharmacology, s. 626-633, 2019.

  • Ibrahim, Moustafa M. A.; Ueckert, Sebastian; Freiberga, Svetlana; Kjellsson, Maria C. et al.

    Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment

    Ingår i AAPS Journal, 2019.

    Open access
  • Ibrahim, Moustafa M. A.; Nordgren, Rikard; Kjellsson, Maria C.; Karlsson, Mats O.

    Variability Attribution for Automated Model Building

    Ingår i AAPS Journal, 2019.

    Open access
  • Wu, Chi-Chih; Klaesson, Axel; Buskas, Julia; Ranefall, Petter et al.

    In situ quantification of individual mRNA transcripts in melanocytes discloses gene regulation of relevance to speciation

    Ingår i Journal of Experimental Biology, 2019.

  • Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

    Correlations between sex-related hormones, alcohol dependence and alcohol craving

    Ingår i Drug And Alcohol Dependence, s. 183-190, 2019.

    Open access
  • Lundberg, Stina; Högman, Cecilia; Roman, Erika

    Adolescent Exploratory Strategies and Behavioral Types in the Multivariate Concentric Square Field (TM) Test

    Ingår i Frontiers in Behavioral Neuroscience, 2019.

    Open access
  • Herman, Stephanie; Åkerfeldt, Torbjörn; Spjuth, Ola; Burman, Joachim et al.

    Biochemical Differences in Cerebrospinal Fluid between Secondary Progressive and Relapsing-Remitting Multiple Sclerosis

    Ingår i Cells, 2019.

    Open access
  • Ryeznik, Yevgen

    Optimal adaptive designs and adaptive randomization techniques for clinical trials

    Open access
  • Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

    A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

    Ingår i ChemistryOpen, s. 114-125, 2019.

    Open access
  • Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

    Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

    Ingår i American Journal of Psychiatry, s. 146-155, 2019.

  • Zetterström, Andreas; Hämäläinen, Markku D.; Karlberg, Elin; Winkvist, Maria et al.

    Maximum Time Between Tests: A Digital Biomarker to Detect Therapy Compliance and Assess Schedule Quality in Measurement-Based eHealth Systems for Alcohol Use Disorder

    Ingår i Alcohol and Alcoholism, s. 70-72, 2019.

  • Toxopeus, Eelke L. A.; de Man, Femke M.; Krak, Nanda; Biermann, Katharina et al.

    Association between Paclitaxel Clearance and Tumor Response in Patients with Esophageal Cancer

    Ingår i Cancers, 2019.

    Open access
  • Ruth, Mike Marvin; Sangen, Jasper J. N.; Remmers, Karlijn; Pennings, Lian J. et al.

    A bedaquiline/clofazimine combination regimen might add activity to the treatment of clinically relevant non-tuberculous mycobacteria

    Ingår i Journal of Antimicrobial Chemotherapy, s. 935-943, 2019.

  • Germovsek, Eva; Osborne, Leanne; Gunaratnam, Flora; Lounis, Shehrazed A. et al.

    Development and external evaluation of a population pharmacokinetic model for continuous and intermittent administration of vancomycin in neonates and infants using prospectively collected data

    Ingår i Journal of Antimicrobial Chemotherapy, s. 1003-1011, 2019.

  • Brekkan, Ari; Lopez-Lazaro, Luis; Plan, Elodie L.; Nyberg, Joakim et al.

    Pharmacokinetic and Pharmacodynamic Sensitivity of Pegfilgrastim

    Ingår i AAPS Journal, 2019.

  • Gustafsson, Sofia; Sehlin, Dag; Lampa, Erik; Hammarlund-Udenaes, Margareta et al.

    Heterogeneous drug tissue binding in brain regions of rats, Alzheimer’s patients and controls: impact on translational drug development

    Ingår i Scientific Reports, 2019.

    Open access
  • Kinch, Amelie; Sundström, Christer; Baecklund, Eva; Backlin, Carin et al.

    Expression of PD-1, PD-L1, and PD-L2 in posttransplant lymphoproliferative disorder after solid organ transplantation

    Ingår i Leukemia and Lymphoma, s. 376-384, 2019.

    Open access
  • Svensson, Robin J.

    Pharmacometric Models to Improve the Treatment and Development of Drugs against Tuberculosis

    Open access
  • Kensert, Alexander; Harrison, Philip J; Spjuth, Ola

    Transfer Learning with Deep Convolutional Neural Networks for Classifying Cellular Morphological Changes

    Ingår i SLAS discovery : advancing life sciences R & D, s. 466 466-475 475, 2019.

    Open access
  • Ibrahim, Moustafa M. A.; Largajolli, Anna; Kjellsson, Maria C.; Karlsson, Mats

    Translation between two models; Application with integrated glucose homeostasis models

    Ingår i Pharmaceutical research, 2019.

    Open access
  • Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

    Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

    Ingår i Restorative Neurology and Neuroscience, s. 87-96, 2019.

    Open access
  • Peters, Kristian; Bradbury, James; Bergmann, Sven; Capuccini, Marco et al.

    PhenoMeNal: Processing and analysis of metabolomics data in the cloud

    Ingår i GigaScience, 2019.

    Open access
  • Germovsek, Eva; Ambery, Claire; Yang, Shuying; Beerahee, Misba et al.

    A Novel Method for Analysing Frequent Observations from Questionnaires in Order to Model Patient-Reported Outcomes: Application to EXACT (R) Daily Diary Data from COPD Patients

    Ingår i AAPS Journal, 2019.

    Open access
  • Maarbjerg, Sabine F.; Thorsted, Anders; Kristoffersson, Anders; Friberg, Lena E. et al.

    Piperacillin pharmacokinetics and target attainment in children with cancer and fever: Can we optimize our dosing strategy?

    Ingår i Pediatric Blood & Cancer, 2019.

  • van Beek, Stijn W.; ter Heine, Rob; Keizer, Ron J.; Magis-Escurra, Cecile et al.

    Personalized Tuberculosis Treatment Through Model-Informed Dosing of Rifampicin

    Ingår i Clinical Pharmacokinetics, s. 815-826, 2019.

    Open access
  • Jernerén, Fredrik; Cederholm, Tommy; Refsum, Helga; Smith, A. David et al.

    Homocysteine Status Modifies the Treatment Effect of Omega-3 Fatty Acids on Cognition in a Randomized Clinical Trial in Mild to Moderate Alzheimer's Disease: The OmegAD Study

    Ingår i Journal of Alzheimer's Disease, s. 189-197, 2019.

  • Ibrahim, Moustafa M. A.; Largajolli, Anna; Karlsson, Mats; Kjellsson, Maria C.

    The Integrated Glucose Insulin Minimal Model: An improved version

    Ingår i European Journal of Pharmaceutical Sciences, s. 7-19, 2019.

  • Heldin, Johan; Rubin Sander, Marie; Leino, Mattias; Thomsson, Sara et al.

    Dynamin inhibitors impair platelet-derived growth factor beta-receptor dimerization and signaling

    Ingår i Experimental Cell Research, s. 69-79, 2019.

    Open access
  • Abrantes, João A.

    Pharmacometric Approaches to Improve Dose Individualization Methods in Hemophilia A

    Open access
  • Brekkan, Ari

    Pharmacometric models in the development of biological medicinal products

    Open access
  • Lampa, Samuel; Dahlö, Martin; Alvarsson, Jonathan; Spjuth, Ola

    SciPipe-Turning Scientific Workflows into Computer Programs

    Ingår i Computing in science & engineering (Print), s. 109-113, 2019.

  • Hu, Yang; Gaillard, Pieter J.; De lange, Elizabeth C.M.; Hammarlund-Udenaes, Margareta

    Targeted Brain Delivery of Methotrexate by Glutathione PEGylated Liposomes: How can the Formulation Make a Difference?

    Ingår i European journal of pharmaceutics and biopharmaceutics, s. 197-204, 2019.

  • Arshad, Usman; Chasseloup, Estelle; Nordgren, Rikard; Karlsson, Mats O.

    Development of visual predictive checks accounting for multimodal parameter distributions in mixture models

    Ingår i Journal of Pharmacokinetics and Pharmacodynamics, s. 241-250, 2019.

  • Atis, Muge; Akcan, Ugur; Ugur Yilmaz, Canan; Orhan, Nurcan et al.

    Effects of methyl-beta-cyclodextrin on blood-brain barrier permeability in angiotensin II-induced hypertensive rats

    Ingår i Brain Research, s. 148-155, 2019.

  • Dhillon, Sundeep S.; Torell, Frida; Donten, Magdalena; Lundstedt-Enkel, Katrin et al.

    Metabolic profiling of zebrafish embryo development from blastula period to early larval stages

    Ingår i PLoS ONE, 2019.

    Open access
  • Abrantes, João A.; Jönsson, Siv; Karlsson, Mats; Nielsen, Elisabet I.

    Handling interoccasion variability in model-based dose individualization using therapeutic drug monitoring data

    Ingår i British Journal of Clinical Pharmacology, s. 1326-1336, 2019.

  • Kurland, Siri; Furebring, Mia; Löwdin, Elisabeth; Eliasson, E. et al.

    Pharmacokinetics of Caspofungin in Critically Ill Patients in Relation to Liver Dysfunction: Differential Impact of Plasma Albumin and Bilirubin Levels

    Ingår i Antimicrobial Agents and Chemotherapy, 2019.