Recent publications

  • Grönbladh, Alfhild; Nylander, Erik; Zelleroth, Sofia; Hallberg, Mathias

    Assessing Cell Viability Effects of Opioids in Primary Cortical Cells from Rat.

    Part of Methods in Molecular Biology, p. 171-180, 2021.

  • Nyman, Julia; Guo, Ning; Sandström, Anja; Hallberg, Mathias et al.

    The amino-terminal heptapeptide of the algesic substance P provides analgesic effect in relieving chronic neuropathic pain

    Part of European Journal of Pharmacology, 2021.

  • Wannberg, Johan; Gising, Johan; Lindman, Jens; Salander, Jessica et al.

    N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands

    Part of Bioorganic & Medicinal Chemistry, 2021.

  • Zelleroth, Sofia; Nylander, Erik; Örtenblad, Axel; Stam, Frida et al.

    Structurally different anabolic androgenic steroids reduce neurite outgrowth and neuronal viability in primary rat cortical cell cultures.

    Part of Journal of Steroid Biochemistry and Molecular Biology, 2021.

  • Isaksson, Rebecka; Casselbrant, Anna; Elebring, Erik; Hallberg, Mathias et al.

    Direct stimulation of angiotensin II type 2 receptor reduces nitric oxide production in lipopolysaccharide treated mouse macrophages

    Part of European Journal of Pharmacology, 2020.

    Open access
  • Balgoma, David; Zelleroth, Sofia; Grönbladh, Alfhild; Hallberg, Mathias et al.

    Anabolic androgenic steroids exert a selective remodeling of the plasma lipidome that mirrors the decrease of the de novo lipogenesis in the liver

    Part of Metabolomics, 2020.

    Open access
  • Nylander, Erik; Zelleroth, Sofia; Stam, Frida; Nyberg, Fred et al.

    Growth hormone increases dendritic spine density in primary hippocampal cell cultures

    Part of Growth Hormone & IGF Research, p. 42-47, 2020.

  • Engen, Karin; Reddy Vanga, Sudarsana; Lundbäck, Thomas; Agalo, Faith et al.

    Synthesis, Evaluation and Proposed Binding Pose of Substituted Spiro-Oxindole Dihydroquinazolinones as IRAP Inhibitors

    Part of ChemistryOpen, p. 325-337, 2020.

    Open access
  • Barlow, Nicholas; Reddy Vanga, Sudarsana; Sävmarker, Jonas; Sandström, Anja et al.

    Macrocyclic Peptidomimetics as Inhibitors of Insulin-Regulated Aminopeptidase (IRAP)

    Part of RSC Medicinal chemistry, p. 234-244, 2020.

  • Nyberg, Fred; Hallberg, Mathias

    Growing knowledge: How growth hormone improves learning

    Part of Acta Physiologica, 2020.

  • Vasile, Silvana; Hallberg, Anders; Sallander, Jessica; Hallberg, Mathias et al.

    Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists

    Part of Biomolecules, 2020.

    Open access
  • Mpakali, Anastasia; Saridakis, Emmanuel; Giastas, Petros; Maben, Zachary et al.

    Structural Basis of Inhibition of Insulin-Regulated Aminopeptidase by a Macrocyclic Peptidic Inhibitor

    Part of ACS Medicinal Chemistry Letters, p. 1429-1434, 2020.

  • Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

    Hindlimb motor responses to unilateral brain injury: spinal cord encoding and left-right asymmetry

    Part of Brain communications, 2020.

    Open access
  • Abu Hamdeh, Sami; Ciuculete, Diana-Maria; Sarkisyan, Daniil; Bakalkin, Georgy et al.

    Differential DNA methylation of the genes for amyloid precursor protein, tau and neurofilaments in human traumatic brain injury

    Part of Journal of Neurotrauma, 2020.

  • Seyer, Benjamin; Diwakarla, Shanti; Burns, Peta; Hallberg, Anders et al.

    Insulin-regulated aminopeptidase inhibitor-mediated increases in dendritic spine density are facilitated by glucose uptake

    Part of Journal of Neurochemistry, p. 485-494, 2020.

    Open access
  • Watanabe, Hiroyuki; Nosova, Olga; Sarkisyan, Daniil; Storm Andersen, Marlene et al.

    Ipsilesional versus contralesional postural deficits induced by unilateral brain trauma: a side reversal by opioid mechanism

    Part of Brain Communications, 2020.

    Open access
  • Zelleroth, Sofia; Nylander, Erik; Nyberg, Fred; Grönbladh, Alfhild et al.

    Toxic Impact of Anabolic Androgenic Steroids in Primary Rat Cortical Cell Cultures

    Part of Neuroscience, p. 172-183, 2019.

    Open access
  • Ho, Ada M-C; Geske, Jennifer R.; Bakalkin, Georgy; Winham, Stacey J. et al.

    Correlations between sex-related hormones, alcohol dependence and alcohol craving

    Part of Drug And Alcohol Dependence, p. 183-190, 2019.

    Open access
  • Isaksson, Rebecka; Lindman, Jens; Wannberg, Johan; Sallander, Jessica et al.

    A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode

    Part of ChemistryOpen, p. 114-125, 2019.

    Open access
  • Tay, Nicole; Macare, Christine; Liu, Yun; Ruggeri, Barbara et al.

    Allele-Specific Methylation of SPDEF: A Novel Moderator of Psychosocial Stress and Substance Abuse

    Part of American Journal of Psychiatry, p. 146-155, 2019.

  • Kononenko, Olga; Watanabe, Hiroyuki; Stålhandske, Lada; Zarelius, Ann et al.

    Focal traumatic brain injury induces neuroplastic molecular responses in lumbar spinal cord

    Part of Restorative Neurology and Neuroscience, p. 87-96, 2019.

    Open access
  • Mueller, Christian P.; Chu, Congying; Qin, Liya; Liu, Chunyu et al.

    The Cortical Neuroimmune Regulator TANK Affects Emotional Processing and Enhances Alcohol Drinking: A Translational Study

    Part of Cerebral Cortex, p. 1736-1751, 2019.

    Open access
  • Wallinder, Charlotta; Sköld, Christian; Sundholm, Sara; Guimond, Marie-Odile et al.

    High affinity rigidified AT(2) receptor ligands with indane scaffolds

    Part of MedChemComm, p. 2146-2160, 2019.

    Open access
  • Meng, Weida; Sjöholm, Louise K; Kononenko, Olga; Tay, Nicole et al.

    Genotype-dependent epigenetic regulation of DLGAP2 in alcohol use and dependence.

    Part of Molecular Psychiatry, 2019.

  • Jia, Tianye; Chu, Congying; Liu, Yun; van Dongen, Jenny et al.

    Epigenome-wide meta-analysis of blood DNA methylation and its association with subcortical volumes: findings from the ENIGMA Epigenetics Working Group.

    Part of Molecular Psychiatry, 2019.

  • Duarte, Joana; Fernandes, Elisabete C.; Kononenko, Olga; Sarkisyan, Daniil et al.

    Differential suppression of the ipsi- and contralateral nociceptive reflexes in the neonatal rat spinal cord by agonists of μ-, δ- and κ-opioid receptors

    Part of Brain Research, p. 182-189, 2019.

  • Ruggeri, Barbara; Macare, Christine; Stopponi, Serena; Jia, Tianye et al.

    Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents

    Part of Journal of Child Psychology and Psychiatry and Allied Disciplines, p. 50-658, 2018.

  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Downregulation of the neuronal opioid gene expression concomitantly with neuronal decline in dorsolateral prefrontal cortex of human alcoholics

    Part of Translational Psychiatry, 2018.

    Open access
  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Dynorphin and κ-Opioid Receptor Dysregulation in the Dopaminergic Reward System of Human Alcoholics.

    Part of Molecular Neurobiology, p. 7049-7061, 2018.

    Open access
  • Kononenko, Olga; Mityakina, Irina; Galatenko, Vladimir; Watanabe, Hiroyuki et al.

    Differential effects of left and right neuropathy on opioid gene expression in lumbar spinal cord

    Part of Brain Research, p. 78-83, 2018.

  • Zhang, Mengliang; Watanabe, Hiroyuki; Sarkisyan, Daniil; Thelin, Jonas et al.

    ASYMMETRIC HINDLIMB POSTURE AND WITHDRAW REFLEXES INDUCED BY UNILATERAL BRAIN INJURY ARE ENCODED IN SPINAL CORD

    Part of Journal of Neurotrauma, p. A208-A208, 2018.

  • Watanabe, Hiroyuki; Zhang, Mengliang; Sarkisyan, Daniil; Kononenko, Olga et al.

    Asymmetric Hindlimb Motor Response To Focal Traumatic Brain Injury Is Controlled By Side-Specific Opioid Mechanism

    Part of Journal of Neurotrauma, p. A79-A79, 2018.

  • Lukoyanov, Nikolay; Carvalho, Liliana; Watanabe, Hiroyuki; Zhang, Mengliang et al.

    Contralesional Hindlimb Motor Response Induced By Unilateral Brain Injury: Evidence For Extra Spinal Mechanism

    Part of Journal of Neurotrauma, p. A201-A201, 2018.

  • Nylander, Erik; Zelleroth, Sofia; Nyberg, Fred; Grönbladh, Alfhild et al.

    The Protective and Restorative Effects of Growth Hormone and Insulin-Like Growth Factor-1 on Methadone-Induced Toxicity In Vitro

    Part of International Journal of Molecular Sciences, p. 1-16, 2018.

    Open access
  • Bazov, Igor; Sarkisyan, Daniil; Kononenko, Olga; Watanabe, Hiroyuki et al.

    Neuronal Expression of Opioid Gene is Controlled by Dual Epigenetic and Transcriptional Mechanism in Human Brain

    Part of Cerebral Cortex, p. 3129-3142, 2018.

  • Brolin, Erika; Zelleroth, Sofia; Jonsson, Anna; Hallberg, Mathias et al.

    Chronic administration of morphine using mini-osmotic pumps affects spatial memory in the male rat

    Part of Pharmacology, Biochemistry and Behavior, p. 1-8, 2018.

  • Skogh, Anna; Lesniak, Anna; Sköld, Christian; Karlgren, Maria et al.

    An imidazole based H-Phe-Phe-NH2 peptidomimetic with anti-allodynic effect in spared nerve injury mice

    Part of Bioorganic & Medicinal Chemistry Letters, p. 2446-2450, 2018.

  • Wannberg, Johan; Isaksson, Rebecka; Bremberg, Ulf; Backlund, Maria et al.

    A convenient transesterification method for synthesis of AT2 receptor ligands with improved stability in human liver microsomes

    Part of Bioorganic & Medicinal Chemistry Letters, p. 519-522, 2018.

  • Reddy Vanga, Sudarsana; Sävmarker, Jonas; Ng, Leelee; Larhed, Mats et al.

    Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Aryl Sulfonamides

    Part of ACS Omega, p. 4509-4521, 2018.

    Open access
  • Ahmed, Aisha S.; Gedin, Per; Hugo, Anders; Bakalkin, Georgy et al.

    Activation of NF-kappa B in Synovium versus Cartilage from Patients with Advanced Knee Osteoarthritis: A Potential Contributor to Inflammatory Aspects of Disease Progression

    Part of Journal of Immunology, p. 1918-1927, 2018.

  • Kononenko, Olga; Bazov, Igor; Watanabe, Hiroyuki; Gerashchenko, Ganna et al.

    Opioid precursor protein isoform is targeted to the cell nuclei in the human brain

    Part of Biochimica et Biophysica Acta, p. 246-255, 2017.

  • Sarkisyan, Daniil; Bazov, Igor; Watanabe, Hiroyuki; Kononenko, Olga et al.

    Damaged reward areas in human alcoholics: neuronal proportion decline and astrocyte activation

    Part of Acta Neuropathologica, p. 485-487, 2017.

  • Ahmed, Aisha Siddiqah; Ahmed, Mahmood; Li, Jian; Gu, Harvest F et al.

    Proteasome inhibitor MG132 modulates inflammatory pain by central mechanisms in adjuvant arthritis.

    Part of International journal of rheumatic diseases, p. 25-32, 2017.

  • Bivehed, Erik; Strömvall, Robert; Bergquist, Jonas; Bakalkin, Georgy et al.

    Region-specific bioconversion of dynorphin neuropeptide detected by in situ histochemistry and MALDI imaging mass spectrometry

    Part of Peptides, p. 20-27, 2017.

    Open access
  • Sui, Ping; Watanabe, Hiroyuki; Artemenko, Konstantin; Sun, Wei et al.

    Neuropeptide imaging in rat spinal cord with MALDI-TOF MS: Method development for the application in pain-related disease studies

    Part of European journal of mass spectrometry, p. 105-115, 2017.

  • Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

    Impact of N-methylation of the substance P 1-7 amide on anti-allodynic effect in mice after peripheral administration

    Part of European Journal of Pharmaceutical Sciences, p. 533-540, 2017.

  • Skogh, Anna; Lesniak, Anna; Gaugaz, Fabienne Z.; Svensson, Richard et al.

    Importance of N-and C-terminal residues of substance P 1-7 for alleviating allodynia in mice after peripheral administration

    Part of European Journal of Pharmaceutical Sciences, p. 345-351, 2017.

  • Kononenko, Olga; Galatenko, Vladimir; Andersson, Malin; Bazov, Igor et al.

    Intra- and interregional coregulation of opioid genes: broken symmetry in spinal circuits

    Part of The FASEB Journal, p. 1953-1963, 2017.

  • Brolin, Erika; Johansson, Jenny; Zelleroth, Sofia; Diwakarla, Shanti et al.

    The mRNA expression of insulin-like growth factor-1 (Igf1) is decreased in the rat frontal cortex following gamma-hydroxybutyrate (GHB) administration

    Part of Neuroscience Letters, p. 15-20, 2017.

  • Kalliomäki, Maija-Liisa; Sandblom, Gabriel; Hallberg, Mathias; Grönbladh, Alfhild et al.

    Genetic susceptibility to postherniotomy pain. The influence of polymorphisms in the Mu opioid receptor, TNF-alpha, GRIK3, GCH1, BDNF and CACNA2D2 genes

    Part of Scandinavian Journal of Pain, p. 1-6, 2016.