Latest publications

  • Lekholm, Emilia; Ceder, Mikaela M.; Forsberg, Erica C.; Schiöth, Helgi B. et al.

    Differentiation of two human neuroblastoma cell lines alters SV2 expression patterns

    Part of Cellular & Molecular Biology Letters (Druk), 2021.

    Open access
  • Gandasi, Nikhil R.; Arapi, Vasiliki; Mickael, Michel E.; Belekar, Prajakta A. et al.

    Glutamine Uptake via SNAT6 and Caveolin Regulates Glutamine-Glutamate Cycle

    Part of International Journal of Molecular Sciences, 2021.

    Open access
  • Tripathi, Rekha; Aggarwal, Tanya; Fredriksson, Robert

    SLC38A10 Transporter Plays a Role in Cell Survival Under Oxidative Stress and Glutamate Toxicity

    Part of Frontiers in Bioscience, 2021.

    Open access
  • Aggarwal, Tanya; Patil, Sourabh; Ceder, Mikaela; Hayder, Maher et al.

    Knockdown of SLC38 Transporter Ortholog-CG13743 Reveals a Metabolic Relevance in Drosophila

    Part of Frontiers in Physiology, 2020.

    Open access
  • Ceder, Mikaela M.; Aggarwal, Tanya; Hosseini, Kimia; Maturi, Varun et al.

    CG4928 is vital for renal function in fruit flies and membrane potential in cells: A first in-depth characterization of the putative Solute Carrier UNC93A

    Part of Frontiers in Cell and Developmental Biology CG4928 is vital for renal function in fruit flies and membrane potential in cells, 2020.

    Open access
  • Ceder, Mikaela M.; Lekholm, Emilia; Klaesson, Axel; Tripathi, Rekha et al.

    Glucose Availability Alters Gene and Protein Expression of Several Newly Classified and Putative Solute Carriers in Mice Cortex Cell Culture and D. melanogaster

    Part of Frontiers in Cell and Developmental Biology, 2020.

    Open access
  • Bagchi, Sonchita; Perland, Emelie; Hosseini, Kimia; Lundgren, Johanna et al.

    Probable role for major facilitator superfamily domain containing 6 (MFSD6) in the brain during variable energy consumption

    Part of International Journal of Neuroscience, p. 476-489, 2020.

    Open access
  • Hosseini, Kimia; Lekholm, Emilia; Ahemaiti, Aikeremu; Fredriksson, Robert

    Differentiation of Human Embryonic Stem Cells into Neuron, Cholinergic, and Glial Cells

    Part of Stem Cells International, 2020.

    Open access
  • Tripathi, Rekha; Hosseini, Kimia; Arapi, Vasiliki; Fredriksson, Robert et al.

    SLC38A10 (SNAT10) is Located in ER and Golgi Compartments and Has a Role in Regulating Nascent Protein Synthesis.

    Part of International Journal of Molecular Sciences, 2019.

    Open access
  • Philippot, Gaetan; Forsberg, Erica; Tahan, Caroline; Viberg, Henrik et al.

    A Single delta(9)-Tetrahydrocannabinol (THC) Dose During Brain Development Affects Markers of Neurotrophy, Oxidative Stress, and Apoptosis

    Part of Frontiers in Pharmacology, 2019.

    Open access
  • Fredriksson, Robert; Sreedharan, Smitha; Nordenankar, Karin; Alsiö, Johan et al.

    The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain.

    Part of PLoS Genetics, 2019.

    Open access
  • Philippot, Gaetan; Hallgren, Stefan; Gordh, Torsten; Fredriksson, Anders et al.

    A Cannabinoid Receptor Type 1 (CB1R) Agonist Enhances the Developmental Neurotoxicity of Acetaminophen (Paracetamol)

    Part of Toxicological Sciences, p. 203-212, 2018.

    Open access
  • Hellsten, Sofie V; Tripathi, Rekha; Ceder, Mikaela; Fredriksson, Robert

    Nutritional Stress Induced by Amino Acid Starvation Results in Changes for Slc38 Transporters in Immortalized Hypothalamic Neuronal Cells and Primary Cortex Cells

    Part of Frontiers in Molecular Biosciences, 2018.

    Open access
  • Hellsten, Sofie V.; Hägglund, Maria; Eriksson, Mikaela; Fredriksson, Robert

    The neuronal and astrocytic protein SLC38A10 transports glutamine, glutamate, and aspartate, suggesting a role in neurotransmission

    Part of FEBS Open Bio, p. 730-746, 2017.

    Open access
  • Lekholm, Emilia; Perland, Emelie; Eriksson, Mikaela M.; Hellsten, Sofie V. et al.

    Putative Membrane-Bound Transporters MFSD14A and MFSD14B Are Neuronal and Affected by Nutrient Availability

    Part of Frontiers in Molecular Neuroscience, 2017.

    Open access
  • Perland, Emelie; Hellsten, Sofie V.; Lekholm, Emilia; Eriksson, Mikaela M. et al.

    The Novel Membrane-Bound Proteins MFSD1 and MFSD3 are Putative SLC Transporters Affected by Altered Nutrient Intake

    Part of Journal of Molecular Neuroscience, p. 199-214, 2017.

    Open access
  • Perland, Emelie; Fredriksson, Robert

    Classification Systems of Secondary Active Transporters

    Part of TIPS - Trends in Pharmacological Sciences, p. 305-315, 2017.

  • Hoeber, Jan; König, Niclas; Trolle, Carl; Lekholm, Emilia et al.

    A Combinatorial Approach to Induce Sensory Axon Regeneration into the Dorsal Root Avulsed Spinal Cord

    Part of Stem Cells and Development, p. 1065-1077, 2017.

  • Perland, Emelie; Bagchi, Sonchita; Klaesson, Axel; Fredriksson, Robert

    Characteristics of 29 novel atypical SLCs of MFS type: evolutionary conservation, predicted structure and neuronal co-expression

    Part of Open Biology, 2017.

    Open access
  • Perland, Emelie; Hellsten, Sofie V; Schweizer, Nadine; Arapi, Vasiliki et al.

    Structural prediction of two novel human atypical SLC transporters, MFSD4A and MFSD9, and their neuroanatomical distribution in mice

    Part of PLoS ONE, 2017.

    Open access
  • Vrettou, Maria; Nordenankar, Karin; Segerström, Lova; Wallén-Mackenzie, Åsa et al.

    Vgluts In The Mesocorticolimbic Brain Of Adolescent Outbred Rats Exposed To Alcohol And Nicotine

    Part of Alcohol and Alcoholism, 2017.

  • Hellsten, Sofie V.; Lekholm, Emilia; Ahmad, Tauseef; Fredriksson, Robert

    The gene expression of numerous SLC transporters is altered in the immortalized hypothalamic cell line N25/2 following amino acid starvation

    Part of FEBS Open Bio, p. 249 249-264 264, 2017.

    Open access
  • Syk, Mikaela; Ramklint, Mia; Fredriksson, Robert; Ekselius, Lisa et al.

    Elevated total plasma-adiponectin is stable over time in young women with bulimia nervosa

    Part of European psychiatry, p. 30-36, 2017.

  • Ceder, Mikaela; Lekholm, Emilia; Hellsten, Sofie V; Perland, Emelie et al.

    The Neuronal and Peripheral Expressed Membrane-Bound UNC93A Respond to Nutrient Availability in Mice

    Part of Frontiers in Molecular Neuroscience, 2017.

    Open access
  • Herisson, F. M.; Waas, J. R.; Fredriksson, Robert; Schiöth, Helgi B. et al.

    Oxytocin Acting in the Nucleus Accumbens Core Decreases Food Intake

    Part of Journal of neuroendocrinology (Print), 2016.

  • Wiemerslage, Lyle; Gohel, Priya A.; Maestri, Giulia; Hilmarsson, Torfi G. et al.

    The Drosophila ortholog of TMEM18 regulates insulin and glucagon-like signaling

    Part of Journal of Endocrinology, p. 233-243, 2016.

  • Bagchi, Sonchita; Hellsten, Sofie Victora; Hägglund, Maria; Arapi, Vasiliki et al.

    Characterization of a unique amino acid transporter, SNAT10, in the Golgi apparatus

    2016.

  • Roshanbin, Sahar; Lindberg, Frida; Lekholm, Emilia; Perland, Emelie et al.

    Histological characterization of orphan transporter MCT14 (SLC16A14) shows abundant expression in mouse CNS and kidney

    Part of BMC neuroscience (Online), 2016.

    Open access
  • Williams, Michael; Klockars, Anica; Eriksson, Anders; Voisin, Sarah et al.

    The Drosophila ETV5 homologue Ets96B: Molecular link between obesity and bipolar disorder

    Part of PLOS Genetics, 2016.

    Open access
  • Perland, Emelie; Lekholm, Emilia; Eriksson, Mikaela M.; Bagchi, Sonchita et al.

    The Putative SLC Transporters Mfsd5 and Mfsd11 Are Abundantly Expressed in the Mouse Brain and Have a Potential Role in Energy Homeostasis

    Part of PLoS ONE, 2016.

    Open access
  • Caruso, Vanni; Sreedharan, Smitha; Carlini, Valeria P.; Jacobsson, Josefin A. et al.

    mRNA GPR162 changes are associated with decreased food intake in rat, and its human genetic variants with impairments in glucose homeostasis in two Swedish cohorts

    Part of Gene, p. 139-145, 2016.

  • Hellsten, Sofie Victora; Perland, Emelie; Lekholm, Emilia; Ahmad, Tauseef et al.

    Amino acid deprivation of neuronal cells changes expression levels of numerous transporters from the SLC family, including several members of the SLC38 family

    2016.

  • Krishnan, Arunkumar; Mustafa, Arshi; Almén, Markus Sällman; Fredriksson, Robert et al.

    Evolutionary hierarchy of vertebrate-like heterotrimeric G protein families

    Part of Molecular Phylogenetics and Evolution, p. 27-40, 2015.

  • Nilsson, Emil; Ernst, Barbara; Voisin, Sarah; Sällman Almén, Markus et al.

    Roux-En Y Gastric Bypass Surgery Induces Genome-Wide Promoter-Specific Changes in DNA Methylation in Whole Blood of Obese Patients

    Part of PLoS ONE, 2015.

    Open access
  • Hägglund, Maria G A; Hellsten, Sofie V; Bagchi, Sonchita; Philippot, Gaëtan et al.

    Transport of L-glutamine, L-alanine, L-arginine and L-histidine by the neuron-specific Slc38a8 (SNAT8) in CNS

    Part of Journal of Molecular Biology, p. 1495-1512, 2015.

  • Rask-Andersen, Mathias; Sällman Almén, Markus; Jacobsson, Josefin A; Ameur, Adam et al.

    Determination of obesity associated gene variants related to TMEM18 through ultra-deep targeted re-sequencing in a case-control cohort for pediatric obesity.

    Part of Genetical Research, 2015.

  • Williams, Michael; Eriksson, Anders; Shaik, Muksheed; Voisin, Sarah et al.

    The obesity-linked Nudt3 Drosophila homolog Aps is associated with insulin signalling

    Part of Molecular Endocrinology, p. 1303-1319, 2015.

  • Hamann, Joerg; Aust, Gabriela; Arac, Demet; Engel, Felix B. et al.

    International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G Protein-Coupled Receptors

    Part of Pharmacological Reviews, p. 338-367, 2015.

  • Corell, Mikael; Wicher, Grzegorz; Radomska, Katarzyna J; Dağlıkoca, E Duygu et al.

    GABA and its B-receptor are present at the node of Ranvier in a small population of sensory fibers, implicating a role in myelination

    Part of Journal of Neuroscience Research, p. 285-295, 2015.

  • Caruso, Vanni; Le Greves, Madeleine; Fard, Shahrzad Shirazi; Haitina, Tatjana et al.

    The Orphan G Protein-Coupled Receptor Gene GPR178 Is Evolutionary Conserved and Altered in Response to Acute Changes in Food Intake

    Part of PLoS ONE, 2015.

    Open access
  • Zheleznyakova, Galina Yu; Nilsson, Emil K.; Kiselev, Anton V.; Maretina, Marianna A. et al.

    Methylation Levels of SLC23A2 and NCOR2 Genes Correlate with Spinal Muscular Atrophy Severity

    Part of PLoS ONE, 2015.

    Open access
  • Rask-Andersen, Mathias; Philippot, Gaetan; Moschonis, George; Dedoussis, George et al.

    CDKAL1-Related Single Nucleotide Polymorphisms Are Associated with Insulin Resistance in a Cross-Sectional Cohort of Greek Children

    Part of PLoS ONE, p. e93193-, 2014.

    Open access
  • Caruso, Vanni; Hägglund, Maria G.; Badiali, Luca; Bagchi, Sonchita et al.

    The G protein-coupled receptor GPR162 is widely distributed in the CNS and highly expressed in the hypothalamus and in hedonic feeding areas

    Part of Gene, p. 1-6, 2014.

  • Williams, Michael; Goergen, Philip; Rajendran, Jayasimman; Zheleznyakova, Galina et al.

    Obesity-linked homologues TfAP-2 and Twz establish meal frequency in Drosophila melanogaster

    Part of PLoS Genetics, p. e1004499-, 2014.

    Open access
  • Williams, Michael J; Goergen, Philip; Rajendran, Jayasimman; Klockars, Anica et al.

    Regulation of aggression by obesity-linked genes TfAP-2 and Twz through octopamine signaling in Drosophila

    Part of Genetics, p. 349-362, 2014.

  • Williams, Michael J; Wang, Yi; Klockars, Anica; Lind, Monica et al.

    Exposure to Bisphenol A Affects Lipid Metabolism in Drosophila melanogaster

    Part of Basic & Clinical Pharmacology & Toxicology, p. 414-420, 2014.

  • Caruso, Vanni; Lagerström, Malin C.; Olszewski, Pawel K.; Fredriksson, Robert et al.

    Synaptic changes induced by melanocortin signalling

    Part of Nature Reviews Neuroscience, p. 98-110, 2014.

  • Alsiö, Johan; Rask-Andersen, Mathias; Chavan, Rohit A.; Olszewski, Pawel K. et al.

    Exposure to a high-fat high-sugar diet causes strong up-regulation of proopiomelanocortin and differentially affects dopamine D1 and D2 receptor gene expression in the brainstem of rats

    Part of Neuroscience Letters, p. 18-23, 2014.

  • Brooks, Samantha J; Nilsson, Emil K; Jacobsson, Josefin A; Stein, Dan J et al.

    BDNF polymorphisms are linked to poorer working memory performance, reduced cerebellar and hippocampal volumes and differences in prefrontal cortex in a Swedish elderly population

    Part of PLoS ONE, p. e82707-, 2014.

    Open access
  • Krishnan, Arunkumar; Dnyansagar, Rohit; Almén, Markus Sällman; Williams, Michael J. et al.

    The GPCR repertoire in the demosponge Amphimedon queenslandica: insights into the GPCR system at the early divergence of animals

    Part of BMC Evolutionary Biology, 2014.

    Open access