Pharmaceutical Bioinformatics

Pharmaceutical Bioinformatics

Research focus: Intelligent systems with AI and machine learning in drug discovery and chemical safety

The Pharmaceutical Bioinformatics research group, headed by Associate Professor Ola Spjuth, focuses on mathematical and statistical modeling, informatics and quantitative analysis of pharmacological systems. We develop methods, algorithms and software to study and model pharmaceutical interactions, and a key focus in the group is how artificial intelligence (AI) and machine learning can aid the drug discovery process; e.g. in drug screening and when studying drug toxicity, metabolism and resistance. We combine in silico and in vitro experiments at the cellular level, and have access to a robotized high-content imaging lab connected to a modern IT-infrastructure to manage and analyze large-scale data. We are involved in several national and international consortia and have a tight connection to the pharmaceutical industry, Uppsala University Hospital, and Science for Life Laboratory.

The research group has a dedicated website with more information on the ongoing projects: https://pharmb.io/