Recent publications

  • Rofo, Fadi; Yilmaz, Canan Ugur; Metzendorf, Nicole G.; Gustavsson, Tobias et al.

    Enhanced neprilysin-mediated degradation of hippocampal A beta 42 with a somatostatin peptide that enters the brain

    Part of Theranostics, p. 789-804, 2021.

    Open access
  • Eltahir, mohmo394; Fletcher, E.; Dynesius, L.; Jarblad, J. L. et al.

    Profiling of donor-specific immune effector signatures in response to rituximab in a human whole blood loop assay using blood from CLL patients

    Part of International Immunopharmacology, 2021.

    Open access
  • Meier, Silvio R.; Sehlin, Dag; Hultqvist, Greta; Syvänen, Stina

    Pinpointing Brain TREM2 Levels in Two Mouse Models of Alzheimer's Disease

    Part of Molecular Imaging and Biology, 2021.

    Open access
  • Georganaki, Maria; Ramachandran, Mohanraj; Tuit, Sander; Nunez, Nicolas Gonzalo et al.

    Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy

    Part of Oncoimmunology, 2020.

    Open access
  • Rostedt Punga, Anna; Strömme, Maria; Alimohammadi, Mohammed; Eltahir, Mohammed et al.

    Flodvåg av långtidssjuka covid-19-patienter väntar

    Part of Dagens Nyheter, p. 5-5, 2020.

  • Eltahir, Mohamed; Persson, Helena; Mangsbo, Sara

    Tumor localized agonistic anti-CD40 therapy and beyond

    Part of Expert Opinion on Biological Therapy, p. 215-217, 2020.

  • Nasi, Aikaterini; McArdle, Stephanie; Gaudernack, Gustav; Westman, Gabriel et al.

    Reactive oxygen species as an initiator of toxic innate immune responses in retort to SARS-CoV-2 in an ageing population, consider N-acetylcysteine as early therapeutic intervention

    Part of Toxicology reports, p. 768-771, 2020.

    Open access
  • Sehlin, Dag; Stocki, Pawel; Gustavsson, Tobias; Hultqvist, Greta et al.

    Brain delivery of biologics using a cross-species reactive transferrin receptor 1 VNAR shuttle.

    Part of The FASEB Journal, p. 13272-13283, 2020.

    Open access
  • Ibarra, Cristian; Karlsson, Marie; Codeluppi, Simone; Varas-Godoy, Manuel et al.

    BCG-induced cytokine release in bladder cancer cells is regulated by Ca2+ signaling

    Part of Molecular Oncology, p. 202-211, 2019.

    Open access
  • Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R.; Antoni, Gunnar et al.

    High detection sensitivity with antibody-based PET radioligand for amyloid beta in brain

    Part of NeuroImage, p. 881-888, 2019.

  • Mangsbo, Sara; Fletcher, Erika; van Maren, Wendy; Redeker, Anke et al.

    Linking T cell epitopes to a common linear B cell epitope: A targeting and adjuvant strategy to improve T cell responses

    Part of Molecular Immunology, p. 115-124, 2018.

  • Fletcher, Erika; van Maren, Wendy; Cordfunke, Robert; Dinkelaar, Jasper et al.

    Formation of Immune Complexes with a Tetanus-Derived B Cell Epitope Boosts Human T Cell Responses to Covalently Linked Peptides in an Ex Vivo Blood Loop System

    Part of Journal of Immunology, p. 87-97, 2018.

  • Eriksson, Jonas; Fang, Xiaotian T.; Hultqvist, Greta; Olberg, D. E. et al.

    [F-18]Tetrazine-trans-cyclooctene mediated labelling of antibodies for PET imaging of amyloid-beta

    Part of European Journal of Nuclear Medicine and Molecular Imaging, p. S643-S643, 2018.

  • Gustafsson, Sofia; Gustavsson, Tobias; Roshanbin, Sahar; Hultqvist, Greta et al.

    Blood-Brain Barrier Integrity in a Mouse Model of Alzheimer’s Disease With or Without Acute 3D6 Immunotherapy

    Part of Neuropharmacology, p. 1-9, 2018.

    Open access
  • Syvänen, Stina; Hultqvist, Greta; Gustavsson, Tobias; Gumucio, Astrid et al.

    Efficient clearence of A beta protofibrils in A beta PP-transgenic mice treated with a brain-penetrating bifunctional antibody

    Part of Alzheimer's Research & Therapy, 2018.

    Open access
  • Jemth, Per; Karlsson, Elin; Vogeli, Beat; Guzovsky, Brenda et al.

    Structure and dynamics conspire in the evolution of affinity between intrinsically disordered proteins

    Part of Science Advances, 2018.

  • Meier, Silvio R.; Syvänen, Stina; Hultqvist, Greta; Fang, Xiaotian T. et al.

    Antibody-Based In Vivo PET Imaging Detects Amyloid-beta Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition

    Part of Journal of Nuclear Medicine, p. 1885-1891, 2018.

    Open access
  • Fletcher, Erika A. K.; Eltahir, Mohamed; Lindqvist, Frida; Rieth, Jonas et al.

    Extracorporeal human whole blood in motion, as a tool to predict first-infusion reactions and mechanism-of-action of immunotherapeutics

    Part of International Immunopharmacology, p. 1-11, 2018.

    Open access
  • Syvänen, Stina; Fang, Xiaotian T.; Hultqvist, Greta; Falting, J. et al.

    Antibody-based PET radioligands for imaging of amyloid-beta protofibrils

    Part of Journal of Cerebral Blood Flow and Metabolism, p. 84-84, 2017.

  • Fang, Xiaotian; Hultqvist, Greta; Meier, Silvio; Sehlin, Dag et al.

    A small bispecific antibody-based construct based on bapineuzumab as a PET tracer for amyloid beta pathology in brain

    Part of Meeting abstract, 2017.

  • Hultqvist, Greta; Syvänen, Stina; Fang, Xiaotian T.; Lannfelt, Lars et al.

    Bivalent Brain Shuttle Increases Antibody Uptake by Monovalent Binding to the Transferrin Receptor

    Part of Theranostics, p. 308-318, 2017.

    Open access
  • Syvänen, Stina; Fang, Xiaotian T.; Hultqvist, Greta; Meier, Silvio R. et al.

    A bispecific Tribody PET radioligand for visualization of amyloid-beta protofibrils - a new concept for neuroimaging

    Part of NeuroImage, p. 55-63, 2017.

    Open access
  • Åberg, Emma; Saccoccia, Fulvio; Grabherr, Manfred; Ore, Wai Ying Josefin et al.

    Evolution of the p53-MDM2 pathway

    Part of BMC Evolutionary Biology, 2017.

    Open access
  • Hultqvist, Greta; Åberg, Emma; Camilloni, Carlo; Sundell, Gustav et al.

    Emergence and evolution of an interaction between intrinsically disordered proteins

    Part of eLIFE, 2017.

    Open access
  • Schiza, Aglaia; Wenthe, Jessica; Mangsbo, Sara; Svensson, Emma et al.

    Adenovirus-mediated CD40L gene transfer increases Teffector/Tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients

    Part of Journal of Translational Medicine, 2017.

    Open access
  • Schiza, Aglaia; Wenthe, Jessica; Mangsbo, Sara; Eriksson, Emma et al.

    Adenovirus-mediated CD40L gene transfer increases teffector/tregulatory cell ratio and upregulates death receptors in metastatic melanoma patients

    Part of Scandinavian Journal of Immunology, p. 337-337, 2017.

  • van Hooren, Luuk; Sandin, Linda C.; Moskalev, Igor; Ellmark, Peter et al.

    Local checkpoint inhibition of CTLA-4 as a monotherapy or in combination with anti-PD1 prevents the growth of murine bladder cancer

    Part of European Journal of Immunology, p. 385-393, 2017.

  • Sehlin, Dag; Hultqvist, Greta; Gumucio, Astrid; Laudon, H. et al.

    Efficient clearance of Amyloid-beta protofibrils in APP-transgenic mice treated with a brain penetrating bifunctional antibody

    Part of Journal of Cerebral Blood Flow and Metabolism, p. 415-416, 2017.

  • Fang, Xiaotian T.; Sehlin, Dag; Lannfelt, Lars; Syvänen, Stina et al.

    Efficient and inexpensive transient expression of multispecific multivalent antibodies in Expi293 cells

    Part of Biological Procedures Online, 2017.

    Open access
  • Loskog, Angelica; Maleka, Aglaia; Mangsbo, Sara; Svensson, Emma et al.

    Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients

    Part of British Journal of Cancer, p. 872-880, 2016.

  • Christiansson, Lisa; Söderlund, Stina; Mangsbo, Sara; Hjorth-Hansen, Henrik et al.

    The Tyrosine Kinase Inhibitors Imatinib and Dasatinib Reduce Myeloid Suppressor Cells and Release Effector Lymphocyte Responses

    Part of Molecular Cancer Therapeutics, p. 1181-1191, 2015.

  • Christiansson, Lisa; Mustjoki, Satu; Simonsson, Bengt; Olsson-Strömberg, Ulla et al.

    The use of multiplex platforms for absolute and relative protein quantification of clinical material

    Part of EuPA Open Proteomics, p. 37-47, 2014.

  • Pedersen, Soren W.; Hultqvist, Greta; Stromgaard, Kristian; Jemth, Per

    The Role of Backbone Hydrogen Bonds in the Transition State for Protein Folding of a PDZ Domain

    Part of PLoS ONE, p. e95619-, 2014.

    Open access
  • Pedersen, Soren W.; Pedersen, Stine B.; Anker, Louise; Hultqvist, Greta et al.

    Probing backbone hydrogen bonding in PDZ/ligand interactions by protein amide-to-ester mutations

    Part of Nature Communications, p. 3215-, 2014.

    Open access
  • Burman, Joachim; Svensson, Emma; Fransson, Moa; Loskog, Angelica et al.

    Tim-3 and PD-1: Regulators of adaptive immunity in multiple sclerosis

    Part of Journal of Neuroimmunology, p. 141-141, 2014.

  • Sandin, Linda; Orlova, Anna; Gustafsson, Erika; Ellmark, Peter et al.

    Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer

    Part of Cancer Immunology Research, p. 80-90, 2014.

    Open access
  • Loskog, Angelica; Maleka, Aglaia; Mangsbo, Sara; Svensson, Emma et al.

    AdCD40L Immunostimulatory Gene Therapy in Combination with Cyclophosphamide Prolongs 6-Months Survival in a Phase I/II Trial for Malignant Melanoma

    Part of Molecular Therapy, p. S247-S247, 2014.

  • Liljenfeldt, Lina; Yu, Di; Chen, Liye; Essand, Magnus et al.

    A Hexon and Fiber-modified Adenovirus Expressing CD40L Improves the Antigen Presentation Capacity of Dendritic Cells

    Part of Journal of immunotherapy (1997), p. 155-162, 2014.

  • Hultqvist, Greta

    Protein Folding, Binding and Evolution: PDZ domains and paralemmins as model systems

    Open access
  • Hultqvist, Greta; Haq, Raza; Punekar, Avinash; Chi, Celestine et al.

    Energetic pathway sampling in a protein interaction domain

    Part of Structure, p. 1193-1202, 2013.

    Open access
  • Eildal, Jonas N. N.; Hultqvist, Greta; Balle, Thomas; Stuhr-Hansen, Nicolai et al.

    Probing the Role of Backbone Hydrogen Bonds in Protein-Peptide Interactions by Amide-to-Ester Mutations

    Part of Journal of the American Chemical Society, p. 12998-13007, 2013.

    Open access
  • Liljenfeldt, Lina; Svensson, E.; Huang, H.; Dieterich, L. et al.

    AdCD40L immunostimulatory gene therapy shifts the MDSC- and macrophage profiles and promotes T cell infiltration in the tumor microenvironment

    Part of Human Gene Therapy, p. A169-A169, 2013.

  • Hultqvist, Greta; Pedersen, Søren; Strømgaard, Kristian; Chi, Celestine et al.

    An expanded view of the protein folding landscape of PDZ domains

    Part of Biochemical and Biophysical Research Communications - BBRC, p. 550-553, 2012.

    Open access
  • Hultqvist, Greta; Punekar, Avinash; Morrone, Angela; Chi, Celestine et al.

    Tolerance of Protein Folding to a Circular Permutation in a PDZ Domain

    Part of PLoS ONE, p. e50055-, 2012.

    Open access
  • Haq, S. Raza; Chi, Celestine N.; Bach, Anders; Dogan, Jakob et al.

    Side-Chain Interactions Form Late and Cooperatively in the Binding Reaction between Disordered Peptides and PDZ Domains

    Part of Journal of the American Chemical Society, p. 599-605, 2012.

    Open access
  • Hultqvist, Greta; Ocampo Daza, Daniel; Larhammar, Dan; Kilimann, Manfred W.

    Evolution of the Vertebrate Paralemmin Gene Family: Ancient Origin of Gene Duplicates Suggests Distinct Functions

    Part of PLoS ONE, p. e41850-, 2012.

    Open access
  • Limbach, Christoph; Laue, Michael M.; Wang, Xiaolu; Hu, Bin et al.

    Molecular in situ topology of Aczonin/Piccolo and associated proteins at the mammalian neurotransmitter release site

    Part of Proceedings of the National Academy of Sciences of the United States of America, p. E392-E401, 2011.

  • Lindqvist, Camilla; Christiansson, Lisa; Thörn, Ingrid; Mangsbo, Sara et al.

    Both CD4(+) FoxP3(+) and CD4(+) FoxP3(-) T cells from patients with B-cell malignancy express cytolytic markers and kill autologous leukaemic B cells in vitro.

    Part of Immunology, p. 296-306, 2011.

  • Mangsbo, Sara; Sandin, Linda; Anger, Kerstin; Korman, Alan et al.

    Enhanced tumor eradication by combining CTLA-4 or PD-1 blockade with CpG therapy

    Part of Journal of immunotherapy (1997), p. 225-235, 2010.

  • Wang, Xiaolu; Hu, Bin; Zieba, Agata; Neumann, Nicole G et al.

    A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1

    Part of Journal of Neuroscience, p. 12584-12596, 2009.